Subclinical carotid vascular disease and risk factors for atherosclerosis in type 1 and type 2 diabetes

Rocha, Viviane Z.; Santos, Raúl D.

doi:10.1590/2359-3997000000264

Cited by 3 publications

(1 citation statement)

References 12 publications

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“…Subclinical vascular disease in type 2 diabetic patients was proved to be assessed by carotid intima media thickness (CIMT) [5][6][7] and the presence of plaques (calcified or not) [8] specially in patients with normal renal function by many researches. The dyslipidemic lipid profile (increased LDL and total cholesterol) usually associated with type 2 diabetes and adds more impact to the process of atherosclerosis process development in these patients [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Role of serum allograft inflammatory factor-1 (AIF-1) in Egyptian type 2 diabetic patients

Eldeeb¹,

Khalil²,

Zaki³

et al. 2020

Clinical Diabetology

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Background. Diabetes mellitus (DM) is a powerful and independent risk factor for cardiovascular disease. The atherosclerosis process in diabetes is indistinguishable from that of the nondiabetic population, but it begins earlier and is often more extensive and more severe. AIF-1 promotes chemotaxis, spreading and migration of macrophages and vascular smooth muscle cells (VS-MCs) which suggest a role of AIF-1 in the atherosclerotic plaque formation. Thus, this study determines the role of AIF-1 in the Egyptian type 2 diabetic patients. Results. The level of AIF-1 was significantly higher in the type 2 diabetic group when compared to the control group (p = 0.000). In type 2 diabetic patients group, there was a significant positive correlation between CIMT and AIF-1 (r = 0.468, p = 0.000). In addition to the positive correlation between CIMT and AIF-1, CIMT in regression model analysis was significantly positive contributing to the outcome variable (AIF-1) (p < 0.05), denoting the possible role of elevated serum AIF-1 level in atherosclerotic process with further studies on larger scale needed.

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Section: Introductionmentioning

confidence: 99%

Role of serum allograft inflammatory factor-1 (AIF-1) in Egyptian type 2 diabetic patients

Eldeeb¹,

Khalil²,

Zaki³

et al. 2020

Clinical Diabetology

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Increased plasma miR-146a levels are associated with subclinical atherosclerosis in newly diagnosed type 2 diabetes mellitus

Guo

Li³

et al. 2020

Journal of Diabetes and its Complications

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A Novel Promising Frontier for Human Health: The Beneficial Effects of Nutraceuticals in Cardiovascular Diseases

Carrizzo

Izzo

Forte

et al. 2020

IJMS

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Cardiovascular diseases (CVDs) such as hypertension, atherosclerosis, myocardial infarction, and diabetes are a significant public health problem worldwide. Although several novel pharmacological treatments to reduce the progression of CVDs have been discovered during the last 20 years, the better way to contain the onset of CVDs remains prevention. In this regard, nutraceuticals seem to own a great potential in maintaining human health, exerting important protective cardiovascular effects. In the last years, there has been increased focus on identifying natural compounds with cardiovascular health-promoting effects and also to characterize the molecular mechanisms involved. Although many review articles have focused on the individual natural compound impact on cardiovascular diseases, the aim of this manuscript was to examine the role of the most studied nutraceuticals, such as resveratrol, cocoa, quercetin, curcumin, brassica, berberine and Spirulina platensis, on different CVDs.

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Subclinical carotid vascular disease and risk factors for atherosclerosis in type 1 and type 2 diabetes

Cited by 3 publications

References 12 publications

Role of serum allograft inflammatory factor-1 (AIF-1) in Egyptian type 2 diabetic patients

Role of serum allograft inflammatory factor-1 (AIF-1) in Egyptian type 2 diabetic patients

Increased plasma miR-146a levels are associated with subclinical atherosclerosis in newly diagnosed type 2 diabetes mellitus

A Novel Promising Frontier for Human Health: The Beneficial Effects of Nutraceuticals in Cardiovascular Diseases

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