Abstract:Background. Diabetes mellitus (DM) is a powerful and independent risk factor for cardiovascular disease. The atherosclerosis process in diabetes is indistinguishable from that of the nondiabetic population, but it begins earlier and is often more extensive and more severe. AIF-1 promotes chemotaxis, spreading and migration of macrophages and vascular smooth muscle cells (VS-MCs) which suggest a role of AIF-1 in the atherosclerotic plaque formation. Thus, this study determines the role of AIF-1 in the Egyptian … Show more
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