Screening of plants found in Amazonas State for lethality towards brine shrimp

Quignard, Etienne Louis Jacques; Pohlit, Adrian Martin; Nunomura, Sergio Massayoshi; Pinto, Ana Cristina da Silva; Santos, Elba Vieira Mustafa dos; Morais, Sabrina Kelly Reis de; Alecrim, Alexandre Mascarenhas; Pedroso, Andreza Cristiana da Silva; Cyrino, Barbara Rachel Brito; Melo, Christiane Santana de; Finney, Ellen Kathryn; Gomes, Erika de Oliveira; Souza, Katiúscia dos Santos de; Oliveira, Lívia Costa de; Don, Luciana de Castro; Silva, Luiz Francisco Rocha e; Queiroz, Maria Mireide Andrade; Henrique, Marycleuma Campos; Santos, Mírian dos; Pinto, Patrícia de Souza; Silva, Suniá Gomes

doi:10.1590/1809-4392200331104

Cited by 52 publications

(36 citation statements)

References 10 publications

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“…However, this indicates that fucoidan possessed the inhibitory and bactericidal effect against the above mentioned human bacterial pathogens. Nowadays, the brine shrimp assay is considered as an excellent method for preliminary investigations of toxicity, to several bioactive molecules from various sources (Quignard et al, 2003). Interestingly, Parra et al, (2001) reported that, the toxic effect of medicinal plants was positively correlated between the lethality to brine shrimp and the corresponding oral lethal dose in mice.…”

Section: Resultsmentioning

confidence: 99%

Antibacterial effect of fucoidan from Sargassum wightii against the chosen human bacterial pathogens

Marudhupandi

Kumar

2013

Int Curr Pharm J

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The present study was aimed to evaluate the antibacterial capability of fucoidan from Sargassum wightii against the chosen human bacterial pathogens. The major chemical constituents of the extracted fucoidan were analyzed by biochemical methods. It showed that the extracted fucoidan contains 52.86 ± 0.64% of fucose and 29.26 ± 0.83% of sulphate. The antibacterial efficacy was performed by agar well diffusion, minimum inhibitory concentration (MIC) and minimum inhibitory concentration (MBC) method. The maximum antibacterial activity 18.6 ± 0.32 mm was obtained for Vibrio cholera and the minimum activity 8.6 ± 0.26 mm was obtained for Salmonella typhi. Result of this manifested the considerable antibacterial potentiality of fucoidan against human bacterial pathogens. Toxicity of fucoidan was evaluated by brine shrimp toxicity assay. No toxic effect was observed in fucoidan. Our study concluded that fucoidan might be used as natural and safe antibiotics in curing many bacterial diseases. Further study is required to get the better understanding of mode of action of fucoidan against the bacterial pathogens.DOI: http://dx.doi.org/10.3329/icpj.v2i10.16408 International Current Pharmaceutical Journal, September 2013, 2(10): 156-158

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Section: Resultsmentioning

confidence: 99%

Antibacterial effect of fucoidan from Sargassum wightii against the chosen human bacterial pathogens

Marudhupandi

Kumar

2013

Int Curr Pharm J

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“…Dry extracts were deposited in our extract bank at the Coordenação de Pesquisas em Produtos Naturais (CPPN / INPA) where they were stored at -19 ºC. Many of these extracts were screened previously by some of us against larvae of the brine shrimp species Artemia franciscana (Quignard et al, 2003).…”

Section: Methodsmentioning

confidence: 99%

Screening of plants found in the State of Amazonas, Brazil for activity against Aedes aegypti larvae

et al. 2004

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Ethanol, methanol and water extracts representing mostly native plant species found in the Amazon region were prepared, respectively, by maceration, continuous liquid-solid extraction and infusion, followed by evaporation and freeze-drying. The freeze-dried extracts were tested for lethality toward Aedes aegypti larvae at test concentrations of 500 µg / mL. In general, methanol extracts exhibited the greatest larvicidal activity. The following 7 methanol extracts of (the parts of) the indicated plant species were the most active, resulting in 100 % mortality in A. aegypti larvae: Tapura amazonica Poepp. KEY WORDS

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“…The aqueous fraction from ethanol extract of P. ramiflora and the aqueous extract from P. torta were toxic to A. salina (Perfeito et al, 2005). On the other hand, methanol and aqueous extracts from P. caimito bark and P. guianensis roots and wood did not presented toxicity against A. franciscana larvae (Quignard et al, 2003;Libralato et al, 2007).…”

Section: Immunomodulatory Activity and Citoxicitymentioning

confidence: 97%

Genus Pouteria: chemistry and biological activity

Silva¹,

Simeoni²,

Silveira³

2009

Rev. bras. farmacogn.

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RESUMO: "Gênero Pouteria: Química e atividade biológica". O gênero Pouteria pertence à família Sapotaceae e pode ser encontrado em muitos continentes. As plantas desse gênero têm sido utilizadas na construção civil, na alimentação e também na medicina popular. Algumas atividades biológicas são reportadas às espécies desse gênero, tais como, antioxidante, anti-inflamatória, antibacteriana e antifúngica, mas seu real potencial como fonte de novos fármacos ainda é pouco conhecido. Assim, uma revisão sobre a composição química e as atividades biológicas de Pouteria é apresentada, com o intuito de estimular a continuação dos estudos das espécies aqui citadas, e a investigação de outras espécies para as quais não foram encontrados relatos.Unitermos: Pouteria, Sapotaceae, triterpenos, flavonoides, plantas medicinais. ABSTRACT:The genus Pouteria belongs to the family Sapotaceae and can be widely found around the World. These plants have been used as building material, as food, because the eatable fruits, as well as remedies in folk medicine. Some biological activities have been reported to species of this genus such as antioxidant, anti-inflammatory, antibacterial and antifungal. However, the real potential of this genus as source of new drugs or phytomedicines remains unknown. Therefore, a review of the so far known chemical composition and biological activities of this genus is presented to stimulate new studies about the species already reported moreover that species have no reference about chemistry or biological activities could be found until now.

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Screening of plants found in Amazonas State for lethality towards brine shrimp

Abstract: 226 methanol and water extracts representing 74 mainly native plant species found in Amazonas State, Brazil, were tested at a standard concentration of 500 μg/mL for lethality towards larvae of the brine shrimp species Artemia franciscana.

Cited by 52 publications

References 10 publications

Antibacterial effect of fucoidan from Sargassum wightii against the chosen human bacterial pathogens

Antibacterial effect of fucoidan from Sargassum wightii against the chosen human bacterial pathogens

Screening of plants found in the State of Amazonas, Brazil for activity against Aedes aegypti larvae

Genus Pouteria: chemistry and biological activity

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