The Micro, Small and Medium Enterprises (MSMEs) of milkfish presto in Semarang have decreased in terms of quantity and quality. The problems faced are the low levels of productivity due to the internal factors, such as: the quality of Human Resources, limited information on access to capital, innovation, and business networking capabilities; and the external factors, such as: high transaction costs, scarcity of raw materials, the acquisition of formal legality and government policies,. This study raised the prestige of milkfish MSMEs in Semarang because it continued to experience a decline from 2013-2019, amounting to 48.64% due to these internal and external factors. Therefore, the aims of this study is to analyze the effect of labor, business capital, innovation, government policy, and networking capabilities on the performance of young entrepreneurs at milkfish presto MSMEs in Semarang. The source data is used by the collection of questionnaires from 41 respondents of the milkfish presto MSME owners in Semarang. The analytical method using multiple regression by SPSS 21 analysis tools. The results showed that business capital, innovation, government policies, and networking capabilities significantly influence the performance of young entrepreneurs, and labor does not significantly influence the performance of young entrepreneurs. The conclusion of this study is that to improve the performance of young entrepreneurs, it is necessary to encourage increased business capital, innovation, and government policies, as well as networking capabilities