In vitro and in vivo antioxidant activity of the pulp of Jatobá-do-cerrado

Abstract

Dxygen metabolism in cells causes the production of free radicals, which produce damage, including changes in cell structure and function. Antioxidants are substances that, at low concentrations, slow down or prevent oxidation. Fruits and vegetables contribute to the dietary supply of these compounds. The flora of the Cerrado in Brazil has shown to have high levels of bioactive compounds. This study aimed to characterize the antioxidant activity of the pulp of jatobá-do-cerrado in vitro and in vivo. In vitro antioxidant activity of the aqueous, ethanol and aqueous acetone extracts was evaluated by the DPPH method. We determined total phenols by the Folin-Ciocalteu assay and tannins by the Folin-Denis method. In vivo antioxidant potential of the aqueous acetone extract was evaluated by the TBARS technique. The aqueous acetone extract had the highest antioxidant capacity, followed by the aqueous and ethanol extracts. The same pattern occurred in the extraction of phenols and in the extraction of tannins. In vivo administration of the aqueous acetone extract inhibited lipid peroxidation compared to the control group. The inhibition of peroxidation has increased by elevating the dosage concentration of the extracts, demonstrating a significant antioxidant potential in vivo as well as in vitro.

Solvent extraction effects on phytochemical constituents profiles, antioxidant and antimicrobial activities and functional group analysis of Ecballium elaterium seeds and peels fruits

“…The antioxidant activity of the extracts was strongly dependent on the extraction solvent (Arakaki et al, 2016). The choice of extraction solvent is a crucial step for the assessment of antioxidant activity of extracts, since polarity of solvents determines the recovery of natural antioxidants from herbals (Goulas et al, 2012;Galanakis et al, 2013).…”

Nutritional profile, bioactive compounds and antioxidant capacity of jatobá-da-mata (Hymenaea courbaril, var. stilbocarpa) by product

“…The fibrous residue of jatobá-da-mata flour had a high polyphenol concentration, which is close to jatobá-do-cerrado flour content (786 mg GAE/100 g) 9 . Jatobá-da-mata flour is a good source of polyphenols, having a concentration which is close to that reported for hydrocetonic extract of jatobádo-cerrado flour, of 536 mg GAE/100 g 2 , and higher than that of baru pulp flour (292 mg GAE/100 g) 21 .…”

“…The antioxidant potential of the pulp of jatobá-do-cerrado (Hymenaea stigonocarpa Mart.) was investigated by Arakaki et al 9 , who reported high phenolic acid and tannin content, and antioxidant activity estimated by DPPH assay. However, jatobá-damata (Hymenaea courbaril, var.…”

Evaluating the Antifungal Activity of Some Traditional Medicinal Plant Extracts against Alternaria solani (Tomato Early Blight Pathogen) in Ethiopia

“…The yield of methanol extraction increases alongside the solubility of antimicrobial plant components increases (Merveill et al 2017). Several workers have reported that a wide range of significant differences for the yields could be due to various factors such as time of extraction, type and part of plant materials used, extraction of solvent polarities, fineness of powder and extent of dryness (Maharjan et al 2010;Ngeny 2012;Silva et al 2014;Naima et al 2015;Arakaki et al 2016;Felhi et al 2017).…”

“…The previous studies indicated that medicinal plants have different antimicrobial activities depending on extraction solvent, plant types and amount of the presence of bioactive compound (Sequeira et al 2013;Stankovi et al 2015;Bahraminejad et al 2015;Arakaki et al 2016). These plants have huge availability nearly our village and easy preparation method can be used by farmers.…”