Nursing care in childcare services: Acantose nigricans as a marker for metabolic risk

Vieira, Caroline Evelin Nascimento Kluczynik; Mariz, Larissa Soares; Medeiros, Carla Campos Muniz; Enders, Bertha Cruz; Coura, Alexsandro Silva

doi:10.1590/0104-1169.2870.2357

Cited by 8 publications

(13 citation statements)

References 14 publications

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“…Studies in other parts of the world on obese children and adolescents with AN have found FSI to range from 15.4 to 31.4 mIU/L. [92728] However, there are no Indian data on this. We observed a significant correlation between FBS and FSI in obese with AN ( r = 0.422, P = 0.001).…”

Section: Discussionmentioning

confidence: 99%

“…Few studies in the past, comparing AN and non-AN obese adolescents using HOMA1-IR, found significantly higher IR in AN cases (43%–63%). [9181927] We did not have any overweight or obese as controls for comparison. A higher percentage of IR in obese and overweight was found in our study, as we have used HOMA2-IR, which has a lower cut-off than HOMA1-IR.…”

Section: Discussionmentioning

confidence: 99%

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Association of acanthosis Nigricans and insulin resistance in indian children and youth – A HOMA2-IR based cross-sectional study

Nithun

Ranugha

Betkerur

et al. 2019

Indian Dermatol Online J

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Introduction: The American Diabetes Association includes acanthosis nigricans (AN) as an indicator of diabetes mellitus risk in overweight youth entering puberty. Some argue that AN is not an independent predictor of insulin resistance (IR), when body mass index (BMI) is controlled for. There is a paucity of studies on the association of AN and IR among children and young adults from India. Homeostatic model assessment-IR (HOMA2-IR), a computerized updated model, which is supposed to be superior to HOMA1-IR, has rarely been used for quantification of IR. Methods: Sixty cases (irrespective of BMI), aged 2–24 years with AN, and 30 age- and sex-matched normal weight controls were included. A thorough clinical examination and grading of AN was done. BMI, fasting glucose levels, and fasting insulin levels were measured for all. HOMA-IR calculator V.2.2.3 was used to calculate IR. Those with HOMA 2-IR >1.8 were considered insulin-resistant. Lifestyle modifications were advised for patients with IR. Results: The mean HOMA2-IR value in cases and controls was 2.422 and 1.322, respectively, which was statistically significant. Overweight and obese cases had 2.5 and 11.25 times higher risk of having IR, respectively, by logistic regression. The association of AN with IR was found to be statistically significant in normal weight cases when compared with controls ( P = 0.045). Grade 4 of neck severity ( P = 0.007), Grade 3 of neck texture ( P = 0.001), and Grade 4 of axillary severity ( P = 0.001) of AN were found to be significantly associated with IR. Limitations: The relatively small sample size may not reflect the accuracy of AN as a marker of IR. Conclusion: Acanthosis nigricans is associated with IR in both normal and obese. We propose that all children, adolescents, and youth with AN be screened for IR irrespective of BMI. Early identification and prompt lifestyle interventions may prevent or delay the onset of diabetes later.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Association of acanthosis Nigricans and insulin resistance in indian children and youth – A HOMA2-IR based cross-sectional study

Nithun

Ranugha

Betkerur

et al. 2019

Indian Dermatol Online J

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“…Dos artículos abordaban enfermedades específi cas: escabiosis 45 y otro Acantose nigricans 46 como instrumento para la enfermería identifi car adolescentes con riesgo metabólico. Sin embargo, en las prácticas de puericultura, los resultados de los estudios están asociados a las enfermedades específi cas y no al desarrollo típico, como se pretende en este estudio.…”

Section: Resultados Y Discusión Figura 2 Temas Abordados En Los Artíunclassified

Puericultura: Una Revisión Sistemática De La Literatura

Ferreira¹,

Pinheiro²,

Azzi³

et al. 2019

SDH

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A puericultura é definida como um conjunto de técnicas utilizadas para avaliar o desenvolvimento físico e mental de crianças, desde a gestação até os quatro ou cinco anos de idade. Este estudo tem por objetivo identificar e descrever os modelos de puericultura encontrados na literatura, especificamente, nas bases de dados MEDLINE, LILACS, LILACS-Express, SCIELO, BDENF, HISA, SESSP-IBPROD, INDEX PSICOLOGIA, PUBMED, PDQ, LEYES, CUIDEN e PROQUEST, utilizando-se o descritor “puericultura” em português e em inglês entre 2010 e 2016. O método utilizado para realizar essa pesquisa foi a revisão sistemática da literatura, e a partir dela, produzir uma leitura cuidadosa das referências encontradas, buscando avaliar a qualidade do estudo e utilizar todas as informações definidas no planejamento. Foi realizada uma síntese narrativa com uma análise quantitativa e qualitativa da mostra bibliográfica, acompanhada pela discussão crítica do material. Os resultados demonstram que não há, em nenhuma referência utilizada, a descrição das práticas realizadas. Observou-se predominância do exercício da puericultura entre enfermeiros. No entanto, médicos e dentistas apareceram entre os estudos analisados, porém focados em áreas específicas, tais como: saúde bucal, desmame precoce, importância da vacinação e desenvolvimento neurocognitivo das crianças. Essa ação tem como consequência prática a compartimentalização do conhecimento sobre a criança, não tendo uma visão abrangente do indivíduo.

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“…Obesity is a multifactorial condition involving genetic and environmental components [1] that represent a public health problem since it affects different populations, regardless of stage of life and socioeconomic status [2]. In Brazil, the Brazilian Institute of Geography and Statistics (IBGE) indicates that among children aged 5 -9 years, one in three is overweight, 14.3% of them are obese [3].…”

Section: Introductionmentioning

confidence: 99%

“…This physical condition is considered the most relevant nutritional problem among children [1], since individuals with a prevalence of fat in body composition are more likely to develop chronic degenerative diseases [5]. The more intense and early development of obesity, the greater the risk of persistence and severity of co-morbidities, such as cardiovascular disease, hypertension, diabetes and some types of cancers [2].…”

Section: Introductionmentioning

confidence: 99%

Lipoprotein (a) and Ultrasensitive C-Reactive Protein in Overweight Adolescents

Alves¹,

Farias²,

Costa³

et al. 2014

Health

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2350= 0.273, p < 0.01) of u-CRP with BMI, which was not verified for lipoprotein (a). Conclusion: As a cardiovascular risk marker already established in literature, the association of u-CRP with the nutritional status of adolescents, proportionally, shows the need for losing weight in this population, especially at early age. A deeper and long-term investigation should be carried out for more effective and consistent contribution to public health.

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Nursing care in childcare services: Acantose nigricans as a marker for metabolic risk

Cited by 8 publications

References 14 publications

Association of acanthosis Nigricans and insulin resistance in indian children and youth – A HOMA2-IR based cross-sectional study

Association of acanthosis Nigricans and insulin resistance in indian children and youth – A HOMA2-IR based cross-sectional study

Puericultura: Una Revisión Sistemática De La Literatura

Lipoprotein (a) and Ultrasensitive C-Reactive Protein in Overweight Adolescents

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