Pre- And Postoperative in Bariatric Surgery: Some Biochemical Changes

Tedesco, Amanda Kaseker; Biazotto, Rafaela; Gebara, Telma Souza e Silva; Cambi, Maria Paula Carlini; Baretta, Giórgio Alfredo Pedroso

doi:10.1590/0102-6720201600s10017

Cited by 7 publications

(6 citation statements)

References 26 publications

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“…Similarly, other reports have found a clear downward trend in BMI post-BS. [20] Our results showed successful weight loss (defined as ≥ 50% EWL) among participants over 1 year. At 6 months postoperatively, 56.8% of the participants successful EWL, and at 9 months, 83.3% had successful EWL.…”

Section: Discussionsupporting

confidence: 51%

Factors influencing body weight one year after bariatric surgery

et al. 2023

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The significant outcome of bariatric surgery (BS) is weight loss, which may be affected by many factors, such as initial body weight before surgery, sex, and dietary intake. Moreover, rapid weight loss is associated with an increased incidence of postsurgical cholelithiasis. To investigate the observed weight loss outcomes during the first year after BS, we investigated the factors that may influence weight loss and to detect the efficacy of prophylactic ursodeoxycholic acid against gallstone formation. This was a retrospective cohort study of all patients with morbid obesity who underwent BS in the hospital and completed a 1-year follow up. Patients with a previous BS or a history of cholecystectomy before BS were excluded. Data were extracted from the medical records at multiple postoperative intervals. There was significant weight loss in terms of percentage of excess weight loss and reduction in body mass index postoperative. A significant correlation was found between the percent of excess weight loss and age, initial body mass index, and initial weight, but there was no significant correlation with sex or type of surgery. The incidence of postoperative cholecystectomy is almost negligible. A significant association was found between age and weight loss after BS. ursodeoxycholic acid is an effective prophylaxis to decrease the incidence of cholecystectomy after BS.

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Section: Discussionsupporting

confidence: 51%

Factors influencing body weight one year after bariatric surgery

et al. 2023

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“…However, a retrospective cohort study including 163 obese patients demonstrated the reduction in the metain ammation up to 4 years after the bariatric surgery by reporting complete normalization of hs-CRP in 84.0 % of patients in 4 years The intensity of weight loss was also reported to have a signi cant linear effect on change in WBC and change in hs-CRP at long term follow-up (16). Improvements in blood glucose and lipid pro le (TC, LDL-C and TG) is important to reduce major cardiovascular risk factors and it has been well documented in various studies within the 6 months after the surgical intervention (13,17). In our study, a signi cant decrease in TC, LDL and also VLDL has been achieved at the 6th month following LSG.…”

Section: Discussionsupporting

confidence: 68%

“…Surgical treatment of obesity has been shown to be affected in not only weight loss but also in the improvement of metabolic pro le. Following surgical treatment of obesity, decrease in the ongoing in ammatory process has been shown with various serum in ammatory markers, particularly CRP (13,4). LSG is one of the most effective bariatric surgery method in the treatment of obesity.…”

Section: Discussionmentioning

confidence: 99%

The Effects of Laparoscopic Sleeve Gastrectomy on Biochemical and Hematological Parameters in Short Term; Retrospective Review of Laboratory and Radiological Findings

Akyol

Erok²

2021

Preprint

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Obesity, with its many associated diseases, is the fastest growing public health problem worldwide. Obesity related chronic inflammation is the main pathophysiological basis in many obesty related comorbidities. In obesity, hypertrophic growth of adipose tissue is associated with the stimulation of the secretion of inflammatory mediators such as tumor necrosis factor-alpha (TNF-a) and interleukin-6 (IL-6) (2, 3). Continued release of inflammatory mediators leads to chronic inflammation.Inflammatory markers such as neutrophil-lymphocyte ratio (NLR) and platelet / lymphocyte ratio (PLR), which are used as diagnostic and prognostic factors in infectious diseases, have been shown to play an important role in the prognostic evaluations in many diseases. The aim of this study is to retrospectively investigate the changes in these obesty related biochemical and hematological parameters 6 months after laparoscopic sleeve gastrectomy (LSG). In addition we also retrospectively reviewed the findings of abdominal ultrasonography (US) examinations in all patients and computed tomography (CT) findings in patients who had been performed, in terms of postoperative complications. In our study, the improvements in inflamatory markers in addition to glucose and lipid profiles have been showed with a possitive correlation parallel to the change in BMI.

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“…The results are related to sustained weight loss and the improvement or resolution of comorbidities associated with morbid obesity 5 , 29 . However, nutritional deficiencies stemming from food restriction associated with poor nutrient absorption are important issues to consider in the follow-up of these patients 6 , 16 , 19 , 25 .…”

Section: Introductionmentioning

confidence: 99%

Vitamin D Deficiency and Paratohommonium Increase in Late Postoperative Gastric Bypass in Roux-en-Y

Mônaco-Ferreira

Leandro‐Merhi

Aranha³

et al. 2018

ABCD, arq. bras. cir. dig.

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Background : Roux-en-Y gastric bypass patients can experience changes in calcium metabolism and hyperparathyroidism secondary to vitamin D deficiency. Aim : To evaluate nutritional deficiencies related to the calcium metabolism of patients undergoing gastric bypass with a 10-year follow-up. Method : This is a longitudinal retrospective study of patients submitted to Roux-en-Y gastric bypass at a multidisciplinary clinic located in the Brazilian southeast region. The study investigated the results of the following biochemical tests: serum calcium, ionized calcium, vitamin D, and parathormone (PTH). The generalized estimating equations (GEE) determined the nutritional deficiencies using a significance level of 5%. Results : Among the patients who finished the study (120 months), 82.86% (n=29) had vitamin D deficiency, and 41.94% (n=13) had high PTH. Postoperative time had a significant effect on PTH (p=0.0059). The percentages of patients with vitamin D, serum calcium, and ionized calcium deficiencies did not change significantly over time. Conclusion : One of the outcomes was vitamin D deficiency associated with secondary hyperparathyroidism. These findings reaffirm the importance of monitoring the bone metabolism of patients submitted to Roux-en-Y gastric bypass. HEADINGS:Calcium deficiency. Vitamin D deficiency. Secondary hyperparathyroidism.

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Pre- And Postoperative in Bariatric Surgery: Some Biochemical Changes

Cited by 7 publications

References 26 publications

Factors influencing body weight one year after bariatric surgery

Factors influencing body weight one year after bariatric surgery

The Effects of Laparoscopic Sleeve Gastrectomy on Biochemical and Hematological Parameters in Short Term; Retrospective Review of Laboratory and Radiological Findings

Vitamin D Deficiency and Paratohommonium Increase in Late Postoperative Gastric Bypass in Roux-en-Y

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