The Effects of Laparoscopic Sleeve Gastrectomy on Biochemical and Hematological Parameters in Short Term; Retrospective Review of Laboratory and Radiological Findings

Abstract

Obesity, with its many associated diseases, is the fastest growing public health problem worldwide. Obesity related chronic inflammation is the main pathophysiological basis in many obesty related comorbidities. In obesity, hypertrophic growth of adipose tissue is associated with the stimulation of the secretion of inflammatory mediators such as tumor necrosis factor-alpha (TNF-a) and interleukin-6 (IL-6) (2, 3). Continued release of inflammatory mediators leads to chronic inflammation.Inflammatory markers such as neutrophil-lymphocyte ratio (NLR) and platelet / lymphocyte ratio (PLR), which are used as diagnostic and prognostic factors in infectious diseases, have been shown to play an important role in the prognostic evaluations in many diseases. The aim of this study is to retrospectively investigate the changes in these obesty related biochemical and hematological parameters 6 months after laparoscopic sleeve gastrectomy (LSG). In addition we also retrospectively reviewed the findings of abdominal ultrasonography (US) examinations in all patients and computed tomography (CT) findings in patients who had been performed, in terms of postoperative complications. In our study, the improvements in inflamatory markers in addition to glucose and lipid profiles have been showed with a possitive correlation parallel to the change in BMI.