EpiFibro (Brazilian Fibromyalgia Registry): data on the ACR classification and diagnostic preliminary criteria fulfillment and the follow-up evaluation

Martinez, José Eduardo; Paiva, Eduardo S.; Rezende, Marcelo Cruz; Heymann, Roberto Ezequiel; Helfenstein, Milton; Ranzolin, Aline; Provenza, José Roberto; Ribeiro, Luiz Gustavo Gonçalves; Souza, Eduardo José do Rosário e; Feldman, Daniel; Assis, Marcos Renato de

doi:10.1016/j.rbre.2016.09.012

Cited by 8 publications

(8 citation statements)

References 11 publications

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“…O modelo fisiopatológico que melhor descreve a fibromialgia parte da observação de que os aparecimentos dos sintomas dolorosos ocorrem de forma geralmente espontânea, simétrica e num sentido craniocaudal, sugerindo como causa para a síndrome disfunções no sistema nervoso central (Martinez et al, 2017;Wolfe et al, 2010).…”

Section: Fisiopatologiaunclassified

“…Além das queixas dolorosas, vários outros sintomas estão presentes, envolvendo estruturas não pertencentes ao aparelho locomotor, entre elas estão as alterações do sono, cefaleia, parestesia em membros superiores e inferiores, fadiga, queixas gastrintestinais e geniturinárias. Outros sintomas descritos são as alterações psicológicas, como a depressão, níveis elevados de somatização e ansiedade, insatisfação e modificação da percepção do estado de saúde (Martinez et al, 2017;Theoharides et al, 2015).…”

Section: Introductionunclassified

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Efeito de intervenções aquáticas sobre os sintomas da fibromialgia: uma revisão

Bloedow

Silva

Guimarães

2021

RSD

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Introdução: Síndrome da fibromialgia é uma condição idiopática crônica de dor musculoesquelética generalizada que afeta principalmente as mulheres. Objetivo deste estudo é investigar na literatura os efeitos de intervenções aquáticas na fibromialgia em relação a parâmetros físicos e psicológicos, e os principais métodos de avaliação. Métodos: Foi realizada uma pesquisa bibliográfica nos bancos de dados Embase, PubMed e Scielo com os descritores: Fibromyalgia, Fibromyalgia Syndrome, Aquatic exercise e Water exercise, totalizando 23 artigos. Resultados: Terapias aquáticas são recomendadas como tratamento pelos seus benefícios. A imersão na água permite a reprodução de movimentos de maneira segura e variada minimizando os impactos quando comparados aos exercícios no solo. Pacientes com fibromialgia relatam a sensação de relaxamento e alívio dos sintomas, após a prática de atividade em meio aquático. Conclusão: Intervenções aquáticas apresentam-se como recursos terapêuticos eficientes para o tratamento da dor e melhora da qualidade de vida de pessoas com fibromialgia.

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Section: Fisiopatologiaunclassified

Section: Introductionunclassified

Efeito de intervenções aquáticas sobre os sintomas da fibromialgia: uma revisão

Bloedow

Silva

Guimarães

2021

RSD

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“…Management of FMS remains challenging and treatment strategies are required to be multidisciplinary. Among nonpharmacological therapies, nutrition is a promising tool, since oxidative stress and/or an imbalance of nutritional components have demonstrated to play a critical role in the pathophysiology of FMS [2,3]. Objectives: We conducted a pilot study (FATMIA Study) to investigate the efficacy and tolerability of a dietary supplementation (NSC) containing coenzyme Q10, magnesium and tryptophan in FMS patients.…”

Section: Ab0952mentioning

confidence: 99%

Ab0951 the Italian Fibromyalgia Registry: A New Way of Using Routine Real-World Data Concerning Patient-Reported Disease Status in Healthcare Research and Clinical Practice

et al. 2020

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Background:Fibromyalgia (FM), the most frequently encountered cause of widespread musculoskeletal pain, affects an estimated 2% of the general Italian population. However, it is not a homogeneous clinical entity, and a number of interacting factors can influence patient prognosis and the outcomes of standardised treatment programmes. Registries are a source of high-quality data for clinical research, but relating this information to individual patients is technically challenging.Objectives:The aim of this article is to describe the structure and objectives of the first Italian Fibromyalgia Registry (IFR), a new web-based registry of patients with FM.Methods:The IFR was developed to collect, store, and share information electronically entered by physicians throughout Italy who are members of the Italian Society of Rheumatology and have a particular interest in FM. It has a web-based architecture that uses two separate servers and an encryption algorithm to ensure the confidentiality and integrity of the exchanged data. The questionnaires included on the platform are the Revised Fibromyalgia Impact Questionnaire (FIQR), the modified Fibromyalgia Assessment Status (ModFAS), and the Polysymptomatic Distress Scale (PDS).Results:The registry includes data relating to 2,339 patients (93.2% female) who satisfied the 1990 or 2010/2011 American College of Rheumatology Classification Criteria for Fibromyalgia at the time of diagnosis. At the time of this analysis, the patients had a mean age of 51.9 years (SD 11.5) and a mean disease duration of 7.3 years (SD 6.9). The majority were married (71.3%), and generally well educated. The overall median FIQR, ModFAS and PDS scores and 25th-75thpercentiles were respectively 61.16 (41.16-77.00), 8.91 (41.16-77.00), and 19.0 (13.00-24.00). The six highest scoring items indicating the greatest impact of the disease on the patients related to fatigue/energy (7.18), sleep quality (6.87), tenderness (6.69), pain (6.68), stiffness (6.66), and environmental sensitivity (6.35). A high proportion of the responding patients reported experiencing pain in the neck (80.46%), upper back (68.36%), and lower back (75.05%).Conclusion:The IFR is the most comprehensive FM registry in Italy, and provides healthcare professionals with a secure, reliable, and easy-to-use means of monitoring the patients’ clinical progression, treatment history and treatment responses. This can help clinicians to plan patient management, facilitates research study patient recruitment, and provides the participating pain clinics with statistics based on real-world data. It also helps address the Italian Ministry of Health long-term goal of using precision medicine for chronic pain prevention and treatment. It is hoped that the IFR will enhance both scientific research and clinical practice.References:[1]Drolet BC, Johnson KB: Categorizing the world of registries 2008; 41: 1009–20.[2]Martinez JE, Paiva ES, Rezende MC, Heymann RE, Helfenstein M, Ranzolin A, et al.: EpiFibro (Brazilian Fibromyalgia Registry): data on the ACR classification and diagnostic preliminary criteria fulfillment and the follow-up evaluation. 2017; 57: 129–33[3]Whipple MO, McAllister SJ, Oh TH, Luedtke CA, Toussaint LL, Vincent A: Construction of a US fibromyalgia registry using the Fibromyalgia Research Survey criteria. 2013; 6: 398–99[4]Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg D, et al.: The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. 1990; 33: 160–72Disclosure of Interests:None declared

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“…Salaffi 1 , S. Farah 1 , V. Giorgi 2 , P. Sarzi-Puttini 2 on behalf of the Italian Society of Rheumatology (SIR). 1 Università Politecnica delle Marche, Clinical and Molecular Science Deparment, Jesi, Italy; 2…”

Section: Ab0951mentioning

confidence: 99%

Ab0950 effect of Selective Serotonin Reuptake Inhibitors and Serotonin Norepinephrine Reuptake Inhibitors on Bone Mineral Density in Egyption Patients With Primary Fibromyalgia

Gazar

2020

Ann Rheum Dis

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Background:Fibromyalgia is characterized by chronic widespread musculoskeletal pain that often co-exists with sleep disturbances, fatigue, cognitive dysfunction, stiffness and tenderness to palpation at specific tender points.Selective serotonin reuptake inhibitors represent a class of commonly used antidepressants. They act by preventing the reuptake of 5-hydroxytryptamine (5-HT) (Serotonin) through the inhibition of the 5-HT transporter (5-HTT) which is located on the presynaptic neuron, thereby increasing levels of 5-HT within the synaptic cleft and modulating neurochemical signaling.Usage of SSRIs was significantly associated with lumbar spine BMD reduction, particularly for old people.DXA and TBS revealed that usage of SSRIs and SNRI was significantly associated with low BMD (Osteopenia and osteoporosis) specially spine BMD reduction with low TBS (partially degraded and degraded) particularly for old people. Conclusion: the present study provided evidence that usage of SSRIs or SNRI was significantly associated with low BMD (Osteopenia and osteoporosis) specially spine BMD reduction with low TBS (Partially degraded and degraded) particularly for old people and despite low BMD was found in the SRI users; it also found in 1ry fibromyalgia not on SRIs so 1ry fibromyalgia should also be considered as a contributing factor for low BM.Objectives:This work aim to determine the correlation between selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs) usage and bone mineral density (BMD) and trabecular bone score (TBS) changes in primary Fibromyalgia patientMethods:The present cross sectional study was conducted on a Hundred (100) Egyptian patients diagnosed as primary fibromyalgia divided according to drug medication into two 2 groups, 50 patients on SSRIs and 50patients on SNRIs, recruited from Rheumatology, Physical Medicine and Rehabilitation departments at AlHussein and Sayed Galal, Al-Azhar University Hospitals. In addition to another 50 age matched the control group subdivided into 25 primary fibromyalgia patients not on those drugs and 25 healthy individuals selected by nurses and medical staff, after an informed consent from all subjects from June 2018 to December 2018..An approval was obtained from the medical ethics committee of Al-Azhar University before starting this study. All the patients were informed about the study procedures and a written consent was obtained from all of them. The subjects were categorized into three groups. Group A: 50 1ry fibromyalgia patients on SSRI. Group B: 50 1ry fibromyalgia patients on SNRI. Group C: 50 individuals as a the control group subdivided into: group C-1: 25, 1ry fibromyalgia patients non SRIs-users and group C-2: 25) healthy individuals.Results:DXA and TBS revealed that usage of SSRIs and SNRI was significantly associated with low BMD (Osteopenia and osteoporosis) specially spine BMD reduction with low TBS (partially degraded and degraded) particularly for old people. Conclusion: the present study provided evidence that usage of SSRIs or SNRI was significantly associated with low BMD (Osteopenia and osteoporosis) specially spine BMD reduction with low TBS (Partially degraded and degraded) particularly for old people and despite low BMD was found in the SRI users; it also found in 1ry fibromyalgia not on SRIs so 1ry fibromyalgia should also be considered as a contributing factor for low BMDConclusion:The present study provided evidence that usage of SSRIs or SNRI was significantly associated with low BMD (Osteopenia and osteoporosis) specially spine BMD reduction with low TBS (Partially degraded and degraded) particularly for old people and despite low BMD was found in the SRI users; it also found in 1ry fibromyalgia not on SRIs so 1ry fibromyalgia should also be considered as a contributing factor for low BMD. Keywords: SSRI, SNRI, FMS, fibromyalgia, osteoporosis, TBS, BMD, bone mineral density, trabecular bone score.Disclosure of Interests:None declared

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EpiFibro (Brazilian Fibromyalgia Registry): data on the ACR classification and diagnostic preliminary criteria fulfillment and the follow-up evaluation

Cited by 8 publications

References 11 publications

Efeito de intervenções aquáticas sobre os sintomas da fibromialgia: uma revisão

Efeito de intervenções aquáticas sobre os sintomas da fibromialgia: uma revisão

Ab0951 the Italian Fibromyalgia Registry: A New Way of Using Routine Real-World Data Concerning Patient-Reported Disease Status in Healthcare Research and Clinical Practice

Ab0950 effect of Selective Serotonin Reuptake Inhibitors and Serotonin Norepinephrine Reuptake Inhibitors on Bone Mineral Density in Egyption Patients With Primary Fibromyalgia

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