Evaluation of the toxicity and molluscicidal and larvicidal activities of Schinopsis brasiliensis stem bark extract and its fractions

Santos, Carlos César Ribeiro; Santos, André Faro; Almeida, Elis Cristiane Valença de; Dias, Antônio Santos; Damascena, Nicole Prata; Santos, Deisylaine M.; Santos, Matheus Ismerim Silva; Júnior, Karlos Antônio Lisboa Ribeiro; Pereira, Carla Karine Barbosa; Lima, Amanda C.B. de; Shan, Andrea Yu Kwan Villar; Santana, Antônio Euzébio Goulart; Estevam, Charles S.; Araújo, Silvan Silva de

doi:10.1016/j.bjp.2014.07.006

Cited by 19 publications

(11 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…8 ± 2.06 (mg EAT/g), respectively. These results confirm studies previously published with this species [28]. High levels of phenolic compounds were also found in samples of Schinopsis brasiliensis [29], in which 455.81 ± 50.41 mg TAE/g were tannins and 11.29 ± 0.94 mg RE/g were flavonoids.…”

Section: Resultssupporting

confidence: 91%

Chemical Analysis and Evaluation of Antioxidant, Antimicrobial, and Photoprotective Activities of Schinopsis brasiliensis Engl. (Anacardiaceae)

Lima-Saraiva

Oliveira

Oliveira-Júnior

et al. 2017

The Scientific World Journal

View full text Add to dashboard Cite

Schinopsis brasiliensis Engl. is a native plant of Caatinga which has high concentrations of compounds capable of absorbing ultraviolet light, suggesting its potential application for the development of sunscreen preparations. After its identification and collection, this vegetable drug was submitted to a physicochemical analysis through the preparation of ethanolic extract. The phytochemical screening and analysis of extracts were carried out by high-performance liquid chromatography (HPLC) evaluation. The antioxidant activity of the extract was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and β-carotene bleaching test. Inhibitory hemolytic activity and morphological deformation of erythrocytes induced by H2O2 were also demonstrated and the antimicrobial activity was analyzed by the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) method. For the in vitro determination of the sun protection factor (SPF), the spectrophotometric method was used. From the analyses carried out with this species, this plant showed significant results for the antioxidant and antimicrobial activities, as well as sunscreen action. Important flavonoids were identified. These data are an important step for the development of new photoprotective cosmetic with Caatinga species, revealing importance and representing another incentive for the preservation of the species involved and analyzed in the study.

show abstract

Section: Resultssupporting

confidence: 91%

Chemical Analysis and Evaluation of Antioxidant, Antimicrobial, and Photoprotective Activities of Schinopsis brasiliensis Engl. (Anacardiaceae)

Lima-Saraiva

Oliveira

Oliveira-Júnior

et al. 2017

The Scientific World Journal

View full text Add to dashboard Cite

show abstract

“…Leaves and bark extracts from S. brasiliensis have been reported to possess antioxidant and antimicrobial activities (Saraiva et al, 2011), while a stem bark extract from S. brasiliensis and its fractions revealed molluscicidal and larvicidal activities (Santos et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Isolation of antioxidant phenolics from Schinopsis brasiliensis based on a preliminary LC-MS profiling

et al. 2017

View full text Add to dashboard Cite

“…Other studies with S. brasiliensis Engl. showed a separation of phytocompounds when the polarity is increased (Santos et al 2014). No fraction studied presented tannins equivalent to catechin, but the EE showed 15.83 mg/g of tannins.…”

Section: Discussionmentioning

confidence: 86%

Schinopsis brasiliensis Engl. to combat the biofilm-dependents diseases in vitro

Sette‐de‐Souza

Santana

Sousa

et al. 2020

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

Dental caries and periodontal disease are the most prevalent of the biofilmdependent diseases. With numerous side effects on the use of chlorhexidine, the search for new safe therapeutic alternatives for microorganisms involved with these diseases increases every day. This study aimed to evaluate the antimicrobial activity and cytotoxicity of extracts made from the bark of Schinopsis brasiliensis Engl. against five oral microorganisms and analyze their phytochemical and thermal degradation profile. The liquid-liquid partition was performed with hexane, chloroform and ethyl acetate. The identification and quantification of the chemical marker was done. Antimicrobial activity was evaluated based on the minimum inhibitory concentration. The cytotoxicity was analyzed based on the hemolysing potential of the samples. The thermal degradation profile was performed by two different methods. Gallic acid was identified as the main compound of the samples and showed the highest amount in the chloroform fraction. All samples were able to inhibit the growth of the microorganisms tested and showed no cytotoxicity. The ethanol extract absorbs less heat than the fractions. All samples exhibited exothermic peak consistent with degradation of gallic acid. Based on the results, the samples used are potential candidates for use in dental formulations for biofilm control.

show abstract

Evaluation of the toxicity and molluscicidal and larvicidal activities of Schinopsis brasiliensis stem bark extract and its fractions

Cited by 19 publications

References 27 publications

Chemical Analysis and Evaluation of Antioxidant, Antimicrobial, and Photoprotective Activities of Schinopsis brasiliensis Engl. (Anacardiaceae)

Chemical Analysis and Evaluation of Antioxidant, Antimicrobial, and Photoprotective Activities of Schinopsis brasiliensis Engl. (Anacardiaceae)

Isolation of antioxidant phenolics from Schinopsis brasiliensis based on a preliminary LC-MS profiling

Schinopsis brasiliensis Engl. to combat the biofilm-dependents diseases in vitro

Contact Info

Product

Resources

About