1‐Oxa‐7, 8‐benzo‐7, 8‐didehydro‐indolizidin aus 3, 4‐Dihydro‐isochinolin und zur Kenntnis des 1‐Methyl‐3, 4, 5, 6, 7, 8‐hexahydro‐isochinolins

Abstract

Archiv der Pha rmazie 1996. W o l d e m a r S c h n e i d e r und B e r t o l d Niiller Dissertation B. JfdZer, Ksrlsruhe 1960. 2 , Diplomarbeit B. NMicEler, J?reiburg/Rr. 1957.

Electrooxidative Cyclization of Hydroquinolyl Alcohols, Hydroquinolylamines, and Dimethyl Aminomalonates

“…[7] Consequently, the conversion of 4a into several useful derivatives were investigated. [8] Lohray and coworkers were able to obtain 2a in a yield of 56% by reduction of the amide esters.…”

“…δ H (CDCl 3 ) 1.2-1.5 (m, 1H, CH 2 ), 1.7-2.1 (m, 3H, CH 2 ), 2.4-3.4 (m, 3H, CH 2 ), 3.7-4.3 (m, 3H, CH 2 ), 4.6-4.8 (m, 1H, CH), 6.4-6.8 (m, 2H, ArH), 6.9-7.3 11 H 13 NO: 175.0997. 2,3,4,6,7,3] 2953,2795,1734,1456,1437,1273,1233,1200,1150,1084. δ H (CDCl 3 ) 0.95 (d,J 7,3H,CH 3 (15), 112 (81), 111 (100), 96 (23) …”

Isoquinolines. 7. Reaction of ethylene oxide with isoquinolines. Novel isoquinolone and oxazolidine formation

“…1 -Bromo-4-p-nitrophenylisoquinoline (7). A solution of 1.0 g (2.90 mmol) of amine 62a in 60 mL of dry THF was added to a refluxing solution of 1.0 mL (872 mg, 7.5 mmol) of isoamyl nitrite (Aldrich 99%) in 20 mL of dry THF dropwise over the course of 1 h under N2.…”