1% Cyclopentolate Hydrochloride: Another Look at the Time Course of Cycloplegia Using an Objective Measure of the Accommodative Response

Manny, Ruth E.; Fern, Karen D.; Zervas, H J; Cline, Ginger E.; Scott, Susan K.; White, Janis M.; Pass, A F

doi:10.1097/00006324-199308000-00013

Cited by 49 publications

(43 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A amplitude de acomodação tende a ser maior em pacientes mais jovens e com íris muito pigmentadas, sendo estes fatores de maior resistência ao efeito cicloplégico 7,9,15 , sendo necessária maior concentração da droga em uso ou instilações repetidas para se obter o residual de acomodação desejado 7,10 , que varia em torno de 0,50 a 1,25 dioptrias esféricas (DE), sendo que autores como Reinecke aceitam até 2,00 DE 2,6,10 .…”

Section: Estudo Comparativo Da Acomodação Residual Após Instilação Deunclassified

See 1 more Smart Citation

Estudo comparativo da acomodação residual após instilação de colírios de tropicamida a 1%, ciclopentolato a 1% e associação de tropicamida a 1% + ciclopentolato a 1%

Pinheiro¹,

Netto²

2000

Arq. Bras. Oftalmol.

View full text Add to dashboard Cite

Estudo comparativo da acomodação residual após instilação de colírios de tropicamida a 1%, ciclopentolato a 1% e associação de tropicamida a 1% + ciclopentolato a 1%Objetivo: Avaliar a acomodação residual após a instilação de duas drogas cicloplégicas, o ciclopentolato a 1% e a tropicamida a 1% e a associação entre elas.Material e Método: Selecionamos pacientes de 15 a 25 anos, com íris grau 4 e 5 pela classificação de Seddon e sem nenhum tipo de doença ocular, que procuraram de maneira espontânea o ambulatório de Oftalmologia da Santa Casa de São Paulo no período de outubro de 1997 a setembro de 1998.Os 46 pacientes foram submetidos a três exames oftalmológicos completos, em que se testava o potencial de acomodação monocularmente, após a instilação de tropicamida a 1%, com tempo de espera de 20 minutos, ciclopentolato a 1% com tempo de espera de 40 minutos e tropicamida a 1% + ciclopentolato a 1% com intervalo entre as drogas de 5 minutos e com latência de 30 minutos. O intervalo entre os exames era de no mínimo 7 dias.Resultados: Não houve diferença entre os grupos dos emétropes, dos hipermétropes e dos míopes com nenhuma droga instilada (p>0,005). O ciclopentolato a 1 % e a associação entre as drogas proporcionaram menor acomodação residual estatisticamente significante, em comparação com a tropicamida a 1% no grupo dos hipermétropes e dos míopes.Conclusão: O ciclopentolato a 1% e a associação entre as drogas são seguras para o exame refratométrico estático em pacientes jovens, com íris escura e sem doença ocular, pois proporcionaram uma média da acomodação residual em todos os grupos pesquisados de no máximo 1,21 ± 0,7 dioptrias esféricas (DE).Comparative study of residual accommodation after the instillation of the following eye drops: 1% tropicamide, 1% cyclopentolate and 1% tropicamide + 1% cyclopentolate

show abstract

Section: Estudo Comparativo Da Acomodação Residual Após Instilação Deunclassified

“…De acordo com a literatura, só participaram deste estudo pacientes com íris escura, para termos o mesmo comportamento em todos os olhos testados no que se refere à dificuldade para a ação cicloplégica 7,9,12,15 .…”

Section: Comentáriosunclassified

Estudo comparativo da acomodação residual após instilação de colírios de tropicamida a 1%, ciclopentolato a 1% e associação de tropicamida a 1% + ciclopentolato a 1%

Pinheiro¹,

Netto²

2000

Arq. Bras. Oftalmol.

View full text Add to dashboard Cite

show abstract

“…Manny et al studied the time course of cycloplegia by monitoring residual accommodation after application of one drop of cyclopentolate 1% in adults aged 18 to 29 years. 6 They found that the maximum cycloplegic effect occurred at 10 minutes in individuals with light irises and at 30 to 40 minutes in individuals with dark irises. However, they only studied adults, among whom only two were Asian.…”

Section: Discussionmentioning

confidence: 97%

“…This finding supports the finding of Manny et al, who reported that individuals with dark irises showed slightly less dilation than did individuals with light irises, and among all of their subjects, the time course for pupil dilation was not the same as the time course for cycloplegia. 6 Additionally, Ebri et al found that 53% of children treated with cyclopentolate had a pupil diameter of …”

Section: Discussionmentioning

confidence: 99%

“…[2][3][4][5][6][7] The timing has also been reported to show a large difference among adults with different iris colors. 6 Other than the studies by Lin et al 7 and Wang et al, 8 who reported the time of maximum cycloplegia in myopic Taiwanese and hyperopic Chinese children, there is currently no other evidence on the time of maximum cycloplegia in Asian children with brown irises.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises

Pukrushpan¹,

Laojaroenwanit²,

Layanun³

et al. 2016

Journal of American Association for Pediatric Ophthalmology and

View full text Add to dashboard Cite

Purpose: We aimed to 1) determine the time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises, 2) evaluate the correlation between the pupillary reaction and time of maximum cycloplegia, and 3) identify any side effects of the medication. Patients and methods: This was a prospective analytical study involving children aged 5 to 14 years who were attending refraction clinic. Cyclopentolate 1% was instilled three times at 10-minute intervals. The spherical equivalent, pupillary reaction, and pupillary diameter were recorded before the first drop and nine times after the last drop at 10-minute intervals. Side effects were assessed. Time of maximum cycloplegia was determined from the time point at which the 95% confidence interval of the differences between the mean spherical equivalent at each point and its final value at 110 minutes was reached and remained within the equivalence limit (±0.25 D). Results: Sixty children were enrolled in this study. Their mean age was 9.8 years (range: 5-14 years). Time of maximum cycloplegia was reached at 30 minutes after the first instillation of cyclopentolate. A poor correlation was observed between the pupillary reaction and the time of maximum cycloplegia (r=-0.07). The mean pupillary diameter at 30 minutes was 3.7±1.3 mm, and further dilation occurred thereafter. No side effects were observed. Conclusion: In most children, maximum cycloplegia was reached 30 minutes after the first instillation of cyclopentolate. The absence of a pupillary reaction should not be used as an indicator of maximum cycloplegia.

show abstract

The Lens and Accommodation

Skalicky

2016

Ocular and Visual Physiology

View full text Add to dashboard Cite

1% Cyclopentolate Hydrochloride: Another Look at the Time Course of Cycloplegia Using an Objective Measure of the Accommodative Response

Cited by 49 publications

References 0 publications

Estudo comparativo da acomodação residual após instilação de colírios de tropicamida a 1%, ciclopentolato a 1% e associação de tropicamida a 1% + ciclopentolato a 1%

Estudo comparativo da acomodação residual após instilação de colírios de tropicamida a 1%, ciclopentolato a 1% e associação de tropicamida a 1% + ciclopentolato a 1%

Time of maximum cycloplegia after instillation of cyclopentolate 1% in children with brown irises

The Lens and Accommodation

Contact Info

Product

Resources

About