The article describes the current understanding of the takotsubo syndrome concerning the issues of pathogenesis, differential diagnosis with acute coronary syndrome and strategy of management. There is presented our own clinical observation of a patient with an atypical form of cardiac dysfunction and myocardial geometry.
The results of the study of metabolic and infectious factors and immune system parameters connections with vascular wall changes at different stages of atherosclerotic process are presented in the article. The data are based on the results of cluster and correlation analyses. Stable clusters consisted of artery wall parameters, organism contamination, immune system characteristics and metabolic factors were present in all of the examined groups. On the basis of the revealed conformities it is suggested to determine the metabolic syndrome as an infectious-metabolic one which would allow to find new ways of its prophylaxis and treatment.
Chronic non-infectious diseases are the leading cause of premature death according to the WHO data. This review considers the evolution of studying and modern views of domestic and foreign authors on the role of skeletal muscles in maintaining health and preventing chronic non-infectious diseases. An idea regarding the nervous and reflex influence from the working muscles on both individual organs and the body as a whole is presented. The role of myokines, specific proteins produced by skeletal muscles, capable of influencing the state of many organs and systems, is described.