In experiments on mice the study of the radioprotective and radiotherapeutic efficacy of the combined use of the selenium-containing feed additive DAFS-25k and the iodine-containing preparation Monclavit-1 was carried out. It has been shown that intragastric administration of DAFS-25k oil solution 3 hours before the total, external, single exposure to γ-radiation, and the subsequent (in 12 hours) intragastric administration of an aqueous solution of Monclavit-1, increases the survival rate of irradiated animals to 67% versus 17% in the control animals. The mechanisms of radioprotective efficacy are assumed to be the antioxidant activity of selenium compounds in DAFS-25k, normalization of thyroid function and relief of gastrointestinal syndrome due to the pronounced antimicrobial activity of Monclavit-1.
Rabbit breeding is one of the promising branches of animal husbandry, but its development is hampered by various diseases. The problem of the pathogenic influence of parasites of the genus Eimeria on the organism of rabbits at different infective doses is still quite urgent. The study was conducted on hybrids of rabbits of Soviet Chinchilla and Californian breeds at 30 and 45 days of age. Within the framework of the experiment 6 groups of young rabbits were formed by the method of pair-analogs. The one-day old rabbits in the experimental groups were infected with oocysts of the association of Eimeria species E. perforans and E. irresidua at doses of 100 000 (2 groups) and 200 000(2 groups) per head, and in control groups (2 groups) - remained intact throughout the experiment. To analyze the pathogenic effect of parasites determination of meat productivity, veterinary and sanitary assessment of carcasses, linear measurements of intestinal length as well as histological studies of the walls of the small intestine were carried out in rabbits of these age groups. The research results showed that rabbits-hybrids infected at a dose of 100 000 and 200 000 oocysts per head demonstrate significant reduction of the increase in live weight and slaughter yield, despite the preservation of the retail display of the carcasses.
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