In total, 81 nonduplicate gram-positive anaerobic cocci (GPAC) were involved in this study. The GPAC were isolated from samples collected from cancer patients between 2004 and 2014. Species identification was carried out by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS). The majority of isolates were identified as Finegoldia magna (47%) and Peptoniphilus harei (28%). The susceptibility of six species of GPAC was determined for eight antibiotics according to E-test methodology. Furthermore, all isolates were susceptible to imipenem, vancomycin, and linezolid. Susceptibility to penicillin G, amoxicillin/clavulanate, metronidazole, ciprofloxacin, and levofloxacin varied for different species. One Finegoldia magna isolate was multidrug-resistant (i.e., parallel resistance to five antimicrobial agents, including metronidazole, was observed). Two Parvimonas micra isolates were highly resistant to metronidazole (MIC 256 μg/mL) but were sensitive to other tested antibiotics.
The North Kokchetav tectonic zone is located between the Kokchetav HP-UHP metamorphic belt and the Stepnyak zone of Ordovician island arc and oceanic complexes. The Kokchetav zone is a collage of nappes (thrust sheets) that consist of basement gneiss and sedimentary rocks of the Kokchetav microcontinent, granite gneiss, mica schists with eclogite blocks, the Shchuch’e ophiolite, Middle Proterozoic felsic volcanics, and Arenigian siliceous-terrigenous sediments with olistostromes. The latter are of gravity-sliding origin and their clastic material includes quartz-muscovite and quartz-garnet-muscovite schists, gneiss, dolomite, and amphibolite. The sheet boundaries are marked by mylonite and Early Ordovician mica schists (40Ar/39Ar ages of syntectonic muscovite are 489–469 Ma). The North Kokchetav collage of compositionally diverse thrust sheets can be interpreted as a collisional zone. According to geological evidence, tectonic activity in the zone lasted as late as the Middle Ordovician. Syncollisional thrusting in the North Kokchetav zone was coeval with the latest dynamic metamorphic event in the Kokchetav belt. All events of retrograde metamorphism and exhumation of HP and UHP rocks in the belt have Cambrian ages, i.e., the rocks had been exhumed prior to the Early–Middle Ordovician collisions and the related orogeny.
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