The work is based examination and treatment of 65 women of the premenopausal period. Assessment of daily blood pressure was carried out by the daily monitoring of blood pressure (DMBP); the state of central hemodynamics was studied by tetrapolar transthoracic rheography, the cerebral hemodynamics was studied by transcranial dopplerography (TCDH), a comprehensive assessment of the hemostasis system -by standard laboratory methods. "Dry" carbon dioxide baths are an effective method of treatment and rehabilitation of patients with a menopausal syndrome. They improve hemostasis, central and cerebral hemodynamics.
It has been established that, under the conditions of technogenic risk, the risk of the pathology of the gestation period increases, leading to the suffering of the fetus as a result of the development of placental insufficiency, an increase in perinatal losses and infant morbidity. The article presents facts about the features of the course of the gestation period, the status of fetuses and newborns under the influence of adverse environmental factors. The condition of the fetuses was determined on the basis of cardiotocography and ultrasound. In order to assess newborns, the cytokine profile and non-specific factors of body defense were studied. The positive dynamics of indicators of the state of the prenatal fetus was achieved on the inclusion in the complex of therapy of means that promote the elimination of heavy metal salts from the mother's body.
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