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IntroductionThere are some cases of indications of anxiety disorders (AD) that go with mitral valve prolapse (MVP). There is a reduction in the intensity of clinical symptoms after the courses of psychotherapy and anxiolitic treatment (Scordo, 2007).ObjectivesTo assess the psychological well-being rating and dynamics of clinical symptoms in MVP patients with AD receiving long-term integrative psychotherapy.Methods32 MVP patients with AD attended integrative psychotherapy (1-2 sessions per week, individual assessments). Among them 56.3% of patients received psychotherapy in addition to Alprazolam medication. Duration of psychotherapy courses ranged from 5 months to 2 years. The psychotherapy program consisted of the elements of CBT, Gestalt therapy, Interpersonal psychotherapy, and Psychodynamic psychotherapy. Psychological and clinical examinations of the patients were made before and after the therapy courses, and in the follow-up study after 2, 5, and 10 years.Results78.1% of patients that attended psychotherapy demonstrated valid improvements of psychological well-being rating, the reduction of anxiety level, and the application of more effective coping-strategies. Positive dynamics of development of personality reflection, with improved skills of self-regulation, and growing awareness of actual needs and resources of personality – all this was associated with reduction of MVP clinical symptoms such as frequency and intensity of chest pain, psychogenic gastrointestinal disorders, neurogenic hyperventilation syndrome, and tension-type headache. 75% of interviewed patients were reported by the psychiatrist to be in sustained remission.ConclusionsMVP patients with AD receiving psychotherapy showed a certain improvement in psychological well-being rating and characteristics of disease pattern.

Aim. To study the influence of type of behavioral activity on the development of cardiovascular diseases, to evaluate the effect of type of behavior on the frequency of repeated hospitalizations and fatal outcomes after acute coronary syndrome. Materials and methods. The study included 100 patients with acute coronary syndrome who were subsequently divided into groups according to the main disease - acute myocardial infarction and unstable angina. The median age was 62.09±5.46 years, the therapy according to the underlying disease. All patients had anamnesis of previous and concomitant diseases, anthropometric measurements, physical examination, and observation during the next 24 months after inclusion in the study. In dynamics he carried out daily monitoring of electrocardiogramm, daily monitoring of blood pressure, echocardiography. Diagnosis of types of behavioral activity was carried out using the test method "type of behavioral activity" developed on the basis of the questionnaire Jenkins Activity Survey, published in 1974 by C. Jenkins, the Russian-language adaptation was performed in NIPNI Bekhtereva (L.I. Wasserman, N.V. Gumenyuk). Results. In patients with behavioral activity type A more frequent occurrence of diseases such as angina, hypertension, acute myocardial infarction, acute violation of cerebral circulation, type 2 diabetes than in persons with behavior type AB and B. Repeated hospitalizations for unstable blood pressure and unstable angina on the background of standard therapy in patients with type a behavior occur more often than in patients with type AB and B.

Psychological testing using Eysenck Personality Inventory and immunological testing of 75 patients with idiopathic mitral valve prolapse revealed low production of interferon-gamma by blood lymphocytes and a correlation between interferon-gamma production and patient's temperament. Low neuroticism and extroversion scores were found in patients with normal interferon-gamma production. High neuroticism score was detected in 82% patients with lowest interferon-gamma production, which refers these patients to a group at high immunological risk and prompts the use of interferon and/or its inductors in complex therapy of these patients.