It is concluded that the magnitude and extent of the surgical intervention and of the follow-up examination depend on the spread of the neoplasm. The treatment of the B, S, D - type tumours implies the necessity of pre-operative embolization of the vessels feeding the neoplasm.
Performing not only respiratory, but also protective, olfactory, aesthetic and a number of other functions, the nose is an important part of the upper respiratory tract. The mucous membrane of the nasal cavity is the first protective barrier of the body that protects against the effects of adverse environmental factors, carrying out warming, purification and neutralization of the inhaled air. This mission is provided by the activity of the multilayered columnar ciliated epithelium, consisting of three main types of cells: ciliate, goblet and basal. The main protective mechanism in the nasal cavity is mucociliary clearance, carried out by means of nasal mucus and beating of cilia unidirectional towards the nasopharynx with a frequency of up to 1000 per minute. Violation of the integrity and disruption of the physiological functions of the mucous membrane of the nasal cavity leads to the development of pathological processes, which in turn can lead to a failure in the work of other organs and systems of the body. To date, about 16-18% of all diseases of the ENT organs are chronic forms of rhinitis. According to the ICAR classification, which is based on the pathophysiological mechanisms of the development of rhinitis, allergic and non-allergic forms are distinguished. Common to various forms is the effect of certain factors on the mucous membrane of the nasal cavity and, as a consequence, a violation of the mechanisms of its work.One of the forms of chronic rhinitis, caused by thinning of the mucous membrane and severe disorders of mucociliary transport, is atrophic rhinitis. The main symptoms of the disease are dryness, the formation of crusts in the nasal cavity, periodic bleeding. The approach to the treatment of acute and chronic processes against the background of atrophic changes in the nasal cavity should be comprehensive and aimed at restoring the physiological functions of the mucous membrane and the mechanisms of mucociliary transport.
The article deals with the treatment of acute inflammatory diseases of the oropharynx, which are an essential part of ENT pathology and are one of the main therapeutic and diagnostic tasks for an otorhinolaryngologist both on an outpatient basis and at the inpatient stage of medical care. It is known that most acute pharyngeal diseases have a viral etiology, do not have etiotropic treatment, and are treated mainly symptomatically. Nevertheless, many patients are irrationally prescribed systemic antibiotic therapy, which leads to an increase in global antibiotic resistance. There are known patterns of correlation between the practice of irrational prescribing of antibacterial therapy and peaks of antibiotic resistance in different countries. At the same time, local antimicrobials are often prescribed, many of which have a negative effect on the pharyngeal microbiome and contribute to bacterial superinfection. The appointment of this group of drugs is also unjustified, given the viral etiology of the pathological process. Acute infections of the upper respiratory tract, including the pharynx, often occur against the background of violation of mucosal immunity, which is the first barrier in the system of protection against respiratory infections. In the treatment of these diseases, it is important to use drugs that not only have antimicrobial properties, but also stimulate mucosal immunity and reparative processes. The solution in this situation can be the therapeutic use of various factors of local immunity that will not cause antibiotic resistance and bacterial superinfection, but will act synergistically with autologous factors of mucosal protection. This article provides an analysis of prospects of using one of such drugs in inflammatory pharynx diseases.
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