Three pyrimidine derivatives -methyluracil, hydroxymethacil (a new compound), and its lithium salt -were tested in model systems of differing complexity for antioxidant properties in comparison with the well-known antioxidant ionol. Tests for antiradical activity and for effects on spontaneous and Fe2+-ascorbate -or NADPH-dependent lipid peroxidation revealed high antioxidant activity (comparable to that of ionol) of the hydroxymethacil lithium salt.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.