This paper studies of the use of nanocrystalline cerium dioxide with artificially formed bone tissue defects. The results of morphometry confirmed the antialterative effect in the early stages of the reparative process of damaged bone tissue. When using calcium hydroxide with nanodispersed cerium dioxide, the nature of osteogenesis should be characterized as activated. In case of damage to the dentin of the roots of the teeth, dentinogenesis in presence of CeO2 occurs with the formation of a combined dentin and bone regenerates. Little or no studies of dentinogenesis in presence of CeO2 were performed by other researchers.

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The study involved 91 patients (48 women and 43 men), aged from 18 to 70 years with GERD. All patients underwent the clinical dental examination according to a single scheme including general clinical manifestations (nausea, single vomiting, belching, heartburn, pain in the epigastrium and around the navel, and poor appetite) and dental manifestations of GERD. The objective assessment of the dental status of the examined patients included the measurement of the functional parameters of the mixed saliva, buffer capacity (BC) of saliva, and the detection of the nitric oxide metabolites (NOx) content in saliva from the right parotid salivary gland (“SRPSG”) and in blood serum using the indirect method based on the determination of the stable metabolites: nitrates and nitrites using the Griess reaction. It was established that salivation rate among patients with GERD with the prevailing of ACR and SACR was at the lower limit of normal values (0.32 + 0.19 ml/min), and the salivation rate among patients with the prevailing of SALCR was low (0.10 + 0.04 ml/min). The BC of saliva among patients with the prevailing of ACR and SACR was high (9.07 + 1.23 mmol eq/l and 9.40 + 1.71 mmol eq/l, respectively) and was reduced among patients with the prevailing of SALCR (7.63 + 0.18 mmol eq/l). The NOx level in SRPSG among patients with GERD was increased (especially in Group 3 (20.93 + 11.23 umol/l)). The direct correlation between the indicators of sialometry, the level of the BC of saliva, and the NOx level in SRPSG were established during the study.

Aim. Determination of the psychological type of attitude to the patient's illness, depending on gender and age group, which will further improve communication between the patient and the dentist.Materials and methods. This article provides a psychological assessment of patients in relation to diseases of the oral cavity at a dental appointment using the adapted TOBOL technique. This technique is based on typing patients according to certain cognitive characteristics described in the article. For this study, 65 people of older age groups were interviewed.Results. The frst group of attitudes towards the disease included 27 patients (41.5%), the second – 24 (37%), the third – 14 (21.5%). 11 (45.8%) men were assigned to the frst group, 8 (33.3%) men – to the second and 5 (20.9%) – to the third group. Women showed a distribution: 16 (39%) women belonged to the frst group, 16 (39%) – to the second and 9 (22%) – to the third group, respectively. Negative attitude towards dental diseases, reluctance to treat them sharply increases in centenarians.Conclusions. With increasing age, there is a growing tendency towards pessimization and aggression. Sensitized attitudes toward illness, depression, refusal of treatment, or blame-shifting complicate diagnosis and subsequent treatment. To prevent unwanted emotions and improve the quality of communication, the dentist should be guided by an individual approach to these patients, which should be based on the basic principles of ethics and deontology. Only then will dental treatment be effective and complete.