Some evidence exists in supporting the beneficial effects of coenzyme Q10 (CoQ10) on oxidative stress. Since the findings of studies over the impact of CoQ10 supplementation on oxidative stress are contradictory, this study was conducted. The aim was to evaluate CoQ10 supplementation effect on total antioxidant capacity (TAC), malondialdehyde (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) levels using data collected from randomized controlled trials (RCTs). Several databases including PubMed, Web of Science, Google Scholar, and Scopus were comprehensively searched up to 23 January 2019 to identify RCTs. A random-effects model, standardized mean difference (SMD), and 95% confidence interval (CI) were applied for data analysis. According to the meta-analysis results on 19 eligible studies, CoQ10 increased the levels of TAC (SMD = 1.29; 95% CI = 0.35-2.23; p = .007), GPX (SMD = 0.45; 95% CI = 0.17-0.74; p = .002), SOD (SMD = 0.63; 95% CI = 0.29-0.97; p < .0001), and CAT (SMD = 1.67; 95% CI = 0.29-3.10; p = .018) significantly. This supplementation also caused a significant reduction in MDA levels (SMD = −1.12; 95% CI = −1.58 to −0.65; p < .0001). However, the results of SOD and CAT should be stated carefully due to the publication bias. In conclusion, this research indicated that CoQ10 supplementation had beneficial effects on oxidative stress markers. However, further studies are needed to confirm these findings.

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Background: Previous studies showed an association between dietary intakes and psychological disorders. This study aimed to assess the association between dietary intakes and psychiatric disorders in Iran. Methods: In this cross sectional research, the data on 9965 adults were extracted from enrollment phase of Yazd Health Study (YaHS); a population-based cohort study on Iranian adults which was conducted during 2014 to 2016. Data on socio-demographic characteristics, tobacco use, history of chronic disease, and dietary assessment were collected using a validated researcher-made questionnaire. Moreover, anthropometric measurement was conducted. Psychological and physical activity assessments were also performed by depression, anxiety and stress scale questionnaire (DASS 21 items) and the short form of the International Physical Activity Questionnaire (IPAQ) respectively. Finally, multiple logistic regression analysis was used to evaluate relation between dietary intakes and psychological disorders.

Objective: Assessing relationship between low carbohydrate diet (LCD) score and metabolic syndrome (Mets) in Iranian adults. Design: Cross-sectional study Setting: Yazd Health Study and Taghzieh Mardom-e-Yazd study. Participants: Data of 2074 participants were used. Dietary intakes were assessed by a validated semi-quantitative food frequency questionnaire. LCD score was calculated for each person by summing up the assigned scores to deciles of energy percentages from macronutrients. Mets was evaluated using National Cholesterol Education Program Adult Treatment Panel III. Eventually, association between LCD score and Mets was examined using logistic regression. Results: Total Mets prevalence was approximately 40.5%. After adjustment for confounders, subjects in the higher quartile of LCD score had a significant lower chance of Mets versus lower quartile among all participants (Q4 versus Q1: OR: 0.68, 95% CI: 0.50-0.92) and separately in men (Q4 versus Q1: OR: 0.54, 95% CI: 0.34-0.86) and women (Q2 versus Q1: OR: 0.53, 95% CI: 0.34-0.82). Furthermore, more LCD adherence in men reduced abdominal obesity by 47% (Q3 versus Q1OR: 0.53, 95% CI: 0.28-0.99). Low HDL cholesterol was also observed both in the highest quartile of LCD score in all participants (OR: 0.74, 95% CI: 0.56-0.99) and separately in men (OR: 0.63, 95% CI: 0.40-0.98) versus the first quartile. Conclusions: More adherence to LCD might be related to lower chance of Mets and some of its components such as low HDL cholesterol and abdominal obesity specially in men. Further studies are required to confirm the findings.