With the popularity of internet, more and more people try to find friends or dating partners on online dating web sites. Recommending appropriate partners from a large amount of candidates becomes an interesting and challenging problem in the field of recommendation system. Various types of recommendation techniques (e.g., content based recommendation, collaborative filtering and association rule mining) have be proposed to tackle this problem. However most of them ignore the personalization concerns that they (1) mainly consider the hot users or frequent items, (2) cover only a portion of users especially ignoring the long tails, (3) and cannot deal with the cold start problem properly. In this paper, we present a regression based hybrid recommendation system that makes use of matching degree, fancy degree, activity, sincerity, popularity and enthusiasm, to recommend appropriate partners. The experimental evaluation of our recommendation system on a real dating web site shows our strategy is more effective and efficient than its previous version which follows the principle of giving higher priority to the recent active users.
Selenoprotein P (SELENOP) is an extracellular antioxidant, selenium transporter, and hepatokine interfering with glucose and lipid metabolism. To study the association between the circulating SELENOP concentration and glucose and lipid metabolic diseases (GLMDs), including gestational diabetes (GD), metabolic syndrome (MetS), non-alcoholic fatty liver disease, obesity, and type 2 diabetes, as well as the individual markers, a meta-analysis was conducted by searching multiple databases from their establishment through March 2022 and including 27 articles published between October 2010 and May 2021, involving 4033 participants. Participants with GLMDs had higher levels of SELENOP than those without GLMDs (standardized mean difference = 0.84, 95% CI: 0.16 to 1.51), and the SELENOP levels were positively correlated with the markers of GLMDs (pooled effect size = 0.09, 95% CI: 0.02 to 0.15). Subgroup analyses showed that the SELENOP concentrations were higher in women with GD and lower in individuals with MetS than their counterparts, respectively. Moreover, SELENOP was positively correlated with low-density lipoprotein cholesterol, but not with the other markers of GLMDs. Thus, the heterogenicity derived from diseases or disease markers should be carefully considered while interpreting the overall positive association between SELENOP and GLMDs. Studies with a larger sample size and advanced design are warranted to confirm these findings.
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