In this paper, a dielectrophoretic (DEP) micro separator is studied for plasma-blood separation. DEP forces created by non-uniform electric fields are used as deflected forces to deplete blood cells from side walls at a given inlet flow rate ( Qin ). Then one can extract plasma through a microchannel on side wall at certain extraction flow rate ( Qp ). In this experiment, saline isotonic solution is chosen as dilute solution for whole blood. The minimum dilute ratio (whole blood: saline dilute) is found to be 1:3 for DEP to substantially deplete blood cells from side walls. Exraction of plasma from whole blood sample by DEP force is also investigated. Experimental results show blood cells do not enter side channel by DEP force at inlet flow rate Qin =0.5 μ1/ min when plasma extract flow rates is Qp ≤ 0.3 μ1/ min . By calculating pure plasma extraction volume fraction, the efficiency in current experiment can reach as high as 20% if dilute ratio 1:3 of whole blood sample is considered.
Background
Horizontal neck wrinkles develop during the aging process.
Aims
This study assessed the effectiveness of a comprehensive approach to treating horizontal neck wrinkles using non-cross-linked hyaluronic acid injection and smooth absorbable PPDO (Poly p-dioxanon) thread insertion.
Methods
Ten patients with horizontal neck wrinkles were treated with hyaluronic acid injection and thread-lifting. The clinical outcomes were evaluated six months after treatment.
Results
The median global aesthetic improvement scale scores evaluated by plastic surgeons and the patients were 4.3 ± 0.8 (3–5) and 4.1 ± 0.7 (3–5), respectively, at six months post-treatment. Five (50%) patients strongly agreed, and three subjects (30%) agreed that their horizontal neck wrinkles had improved following treatment. No serious adverse events, including infections, lumps, irregularities, or the Tyndall effect, occurred during treatment.
Conclusion
This study revealed that a comprehensive approach using hyaluronic acid and thread-lifting provided satisfactory and effective clinical outcomes in treating horizontal neck wrinkles.
Level of evidence IV
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Background:
Vascular complications from glabellar intravascular filler injections are major safety concerns. Filler injection into the glabella without precise knowledge of its vascular topography poses a risk of severe complications.
Methods:
Computed tomography was used to study 90 cadaveric heads after contrast agent and filler injection, and 15 cadaveric heads were dissected.
Results:
Central (CAs), paracentral (PCAs), and reverse dorsal nasal arteries (rDNAs) were found in 70 (38.9%), 58 (32.2%), and 16 (8.9%) of the 180 hemifaces, respectively. Based on the presence of CAs, PCAs, and rDNAs between the bilateral supratrochlear arteries (STAs), glabellar arteries were categorized into two main patterns: in type 1 [without named arteries between bilateral STAs; 22 of 90 (24.4%)], the glabella was supplied by bilateral STAs and their branches; in type 2 [with named arteries between bilateral STAs; 68 of 90 (75.6%)], the glabella was supplied by bilateral STAs and CAs, PCAs, and rDNAs. Type 2 could be further divided into three subtypes: in type 2a [45 of 90 (50.0%)], the glabella was supplied by bilateral STAs and one of the named arteries; in type 2b [21 of 90 (23.3%)], the glabella was supplied by bilateral STAs and two of the named arteries; and in type 2c [two of 90 (2.3%)], the glabella was supplied by bilateral STAs and unilateral CA, PCA, and rDNA.
Conclusion:
This study elucidated novel arterial systems and proposed considerations for glabellar filler injection.
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