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The effect of static magnetic field (MF) on the growth and biochemical indices of five fungal genera were studied. Exposing the above genera to the northern pole, southern pole and both poles and their influences were compared with the control treatment (without MF energy). The static MF of 10 gauss was applied to the above fungal genera for seven days at 28°C. The effect of static MF energy on the growth of fungal genera on solid media Sabouraud Dextrose Agar (SDA) and Potato Dextrose Agar (PDA) was classified as stimulatory, inhibitory and no observable effect on growth of fungal genera. The effects of MF poles (southern, northern and both) inhibited the growth of Fusarium oxysporum, while the MF poles stimulated the growth of fungal genera (Aspergillus niger, Alternaria alternate and Penicillium chrysogenium) and had no observable effect of southern pole and both poles on growth of Rhizopus oryzae, while the northern pole inhibited the growth of R. oryzae compared with control group by measuring the growth diameter (cm). The effects of MF poles on the biochemical indices of the fungal genera were performed by filtering the growth and measuring the enzyme activity in the filterate. Exposing the fungal genera to the northern pole, southern pole. The fungal genera were influenced by MF energy for 3 days at 28°C and pH6.5 showed increased in the activities of amylase and protease due to northern pole at significant difference (at the 0.05 levels), the northern pole increased amylase activity (U/ml) in the culture medium filteratedof P. chrysogenumup to (0.246 U/ml) higher than other mentioned genera, A. niger, F. oxysporum, R. oryzae and A. alternata 0.172, 0.146, 0.116, 0.105U/ml respectively. The northern pole increased protease activity (U/ml) in the culture filterate of P. chrysogenumup to (0.081 U/ml) higher than other mentioned genera, A. niger, A. alternata , R. oryzae and F. oxysporum 0.08, 0.074, 0.056,0.054U/ml respectively and decreased when treated with southern pole however it was higher than the control treatment under optimum condition.

Background: Breast cancer composed of several biologic subtypes that have response to hormonal therapy. Tamoxifen is  hormonal therapy  with tissue- pecific antagonistic or agonist effects, the latter being responsible for multiple  effects on lipid metabolism in women . Objective: This study was designed to determine the impact of Tamoxifen on the serum lipid profile in breast cancer women.  Patients and methods: Prospective observation cohort study conducted at Oncology Teaching Hospital, Medical city complx.starting from October 2015 to October 2016. A total number of 40 premenopausal women with breast cancer   were enrolled in this study according to inclusion criteria . Patients were followed for three months by the measurements TC, TG, HDL – cholesterol and BMI . Results: At the end of third months of hormonal therapy, Tamoxifen showed a significant decrease in TG, VLDL (p< 0.001 for both).  On the other side HDL and BMI  showed significant increase over three months duration , (p = 0.001  and 0.006, respectively) . Conclusion: Beneficial alterations of lipid profiles were seen in pre-menopausal breast cancer patients treated with Tamoxifen.

No abstract

Background: Breast cancer composed of several biologic subtypes that have response to hormonal therapy. Tamoxifen is hormonal therapy with tissue-pecific antagonistic or agonist effects, the latter being responsible for multiple effects on lipid metabolism in women. Objective: This study was designed to determine the impact of Tamoxifen on the serum lipid profile in breast cancer women. Patients and methods: Prospective observation cohort study conducted at Oncology Teaching Hospital, Medical city complx.starting from October 2015 to October 2016. A total number of 40 premenopausal women with breast cancer were enrolled in this study according to inclusion criteria. Patients were followed for three months by the measurements TC, TG, HDLcholesterol and BMI. Results: At the end of third months of hormonal therapy, Tamoxifen showed a significant decrease in TG, VLDL (p< 0.001 for both). On the other side HDL and BMI showed significant increase over three months duration , (p = 0.001 and 0.006, respectively). Conclusion: Beneficial alterations of lipid profiles were seen in pre-menopausal breast cancer patients treated with Tamoxifen.