Purpose: Our study aimed to investigate the combinatorial effect of vitamin C and E on oxidative stress, the number of folicles, and hormonal level in female rats orally exposed to monosodium glutamate (MSG). Materials and Methods:Female, twelve weeks old Wistar rats ingested with of MSG at dose 140 mg/200 gram body weight (bw) with or without combination of vitamin C and E. Twenty five rats were divided into five group (n = 5 each), control group, MSG-treatment group, MSG-treatment + 0.2 mg/g bw vitamin C + 0.04 IU/g bw vitamin E (MSG + CE1), MSG-treatment + 0.4 mg/g bw vitamin C + 0.04 IU/g bw vitamin E (MSG + CE2), and MSG-treatment + 0.6 mg/g bw vitamin C + 0.04 IU/g bw vitamin E (MSG + CE1). Analysis of malondialdehyde (MDA) level was done colorimetrically. Analysis of the number of ovarian follicles was done histopathologically with hematoxylin eosin staining. Analysis of 17β-estradiol and follicle stimulating hormone (FSH) levels were done by ELISA technique. Results: There were significantly (P < 0.05) increased ovarium MDA levels and atresia follicle number in groups exposed to MSG compared to non-exposure group. The level of FSH, 17β-estradiol, the number of primary, secondary, de Graaf follicles were significantly lower in MSG-treatment group compared to control group (P < 0.05). The administration of combined vitamin C and E (second and third dose) significantly (P < 0.05) decreased the MDA levels and the number of atresia follicle compared to the MSG-exposed groups, to reach level in control group (P > 0.05). MSG + CE2 and MSG + CE3 significantly increased FSH level, number of primary follicles, compared to MSG-treatment group (P < 0.05), to reach similar level in control group (P > 0.05). All dose of combined vitamin C and E significantly increased 17β-estradiol level and the number of secondary and de Graaf follicles compared to MSG-treatment group (P < 0.05), to reach significantly higher level compared to control group (P < 0.05). Conclusion:The present data suggest that combination of vitamin C and E as in this study inhibited ovarium toxicity caused by MSG treatment. Keywords: glutamate; antioxidant; folliculogenesis; hormone; lipid peroxidation Sadece MSG verilmiş grup ile karşılaştırıldıklarında; C ve E vitaminlerinin tüm dozlarının, 17β-estradiol düzeyi ile sekonder ve graff folikül sayılarını anlamlı olarak arttırdıkları tespit edilmiştir (P < 0.05). C ve E vitaminlerinin verildiği gruplarda, 17β-estradiol düzeyi ile sekonder ve graffolikül sayıları, kontrol grubunun üzerindeki düzeylere ulaşmıştır (P < 0.05).Sonuç: Bulgularımız C ve E vitamin kombinesinin MSG'ya maruz kalmaya bağlı olarak gelişen ovaryum toksisitesini inhibe ettiği sonucunu ortaya koymuştur.
: BIAN (Bulan Imunisasi Anak Nasional) dilakukan untuk memberikan imunisasi tambahan Campak/Measles-Rubela pada balita dan melengkapi dosis Imunisasi DPT-HB-Hib dan Polio yang sudah terlewat. Di Indonesia terdapat sekitar delapan ratus ribu anak beresiko lebih besar tertular penyakit yang dapat dicegah dengan vaksin seperti campak, rubella, polio, difteri, dan tetanus. Pemerintah Indonesia berupaya memulihkan cakupan yang hilang akibat gangguan kegiatan imunisasi selama pandemic COVID-19. Kegiatan ini bertujuan untuk mendukung kesuksesan kegiatan Bulan Imunisasi Anak Nasional (BIAN) dengan tercapainya cakupan imunisasi pada anak dan sebagai bentuk pengabdian kepada masyarakat, pada tanggal 12 Agustus 2022 kami dosen kebidanan bekerjasama dengan Puskesmas Kecamatan Sawah Besar Jakarta Pusat melaksanakan pemberian imunisasi pada anak usia 9 bulan - 59 bulan di Posyandu dan tempat layanan vaksin yang telah ditetapkan oleh Puskesmas Kecamatan Sawah Besar Jakarta Pusat. Selain pemberian imunisasi, sosialisasi, dan pemberian edukasi tentang Kesehatan anak juga dilakukan oleh para dosen kebidanan agar dapat meningkatkan cakupan imunisasi di daerah Jakarta Pusat. Hasil dari kegiatan ini berjalan dengan baik dan lancar, anak-anak yang belum mendapatkan imunisasi lengkap sampai usia 9 bulan diberikan imunisasi untuk mengejar ketinggalannya, dan yang sudah lengkap imunisasi wajibnya sampai usia 9 bulan diberikan tambahan imunisasi campak/measles-rubela. Kegiatan ini sebagai upaya dari pemerintah dalam percepatan pencapaian eliminasi Campak dan Rubela melalui kegiatan pemberian imunisasi tambahan secara bertahap.BIAN (National Childhood Immunization Month) is held to provide additional Measles/Measles-Rubella immunization to toddlers and complete the missed DPT-HB-Hib and Polio immunization doses. In Indonesia, around eight hundred thousand children are at greater risk of contracting vaccine-preventable diseases such as measles, rubella, polio, diphtheria, and tetanus. The Indonesian government is working to restore coverage lost due to the disruption of immunization activities during the COVID-19 pandemic. This activity aims to support the success of the National Child Immunization Month (BIAN) by achieving immunization coverage in children and as a form of community service; on August 12 2022, we midwifery lecturers collaborate with the Sawah Besar District Health Center in Central Jakarta to carry out immunizations for children aged 9 months - 59 months at the Posyandu and the location of the vaccine service that the Sawah Besar District Health Center has determined Central Jakarta. In addition to immunizations, outreach and education about child health are also carried out by midwifery lecturers to increase immunization coverage in the Central Jakarta area. The results of this activity went well and smoothly; children who had not received complete immunization by the age of 9 months were given immunizations to catch up, and those who had completed their mandatory immunizations until the age of 9 months were given additional immunization against measles/measles-rubella. This activity is part of the government's efforts to accelerate the achievement of measles and rubella elimination by providing additional immunizations in stages.
Peer support provides many positive impact either for postpartum or breastfeeding mothers. As a new mother, hopefully woman can breasfeeds their baby exclusively and maintain their mental health. All of this can be obtained through peer support. This study is to determine the benefits of peer support to increasing breast milk production and the mental health resilience.This study is a literature riview, by descriptive analysis. The study include 14 articles which were published in 2018-2022, through PubMed, Pro Quest and Google scholar websites. A total of 20,600 articles were found by emerging from keywords, 3,852 articles were selected after screening the title and abstract based on the research theme, 54 articles were selected based on the content and research objectives, until 13 articles that met the research criteria. Research shows the positive impact of peer support on exclusive breastfeeding and postpartum mental health, either offline or online can be effective
Breastfeeding and maternal mental health in the perinatal period are two important issues in public health. Breastfeeding is the most ideal way to feed babies and has positive short and long term impacts for both mothers and babies. Breastfeeding is a natural process, but many mothers experience problems and feel pressured by breastfeeding. Mothers who had high levels of anxiety and/or depression (high scores on psychometric tests that detect mental health disorders) before or during pregnancy or after delivery had more difficulties with breastfeeding than others. The aim of this study was to synthesize the results of current research on the relationship between perinatal mental health and breastfeeding outcomes. This study uses the literature review method. Literature searches used Pubmed, Tandfoline, Science Direct, and Google Scholar in 2018 – 2022. Articles were screened independently by researchers using the PRISMA method. Based on the 11 articles analyzed, it was shown that most of the longitudinal studies showed a relationship between perinatal mental health and breastfeeding outcomes. Other longitudinal studies also explain the existence of a two-way causality relationship between perinatal mental health and breastfeeding outcomes variables. Perinatal mental health influences practice and continuity of breastfeeding. Conversely, the practice and continuity of breastfeeding also affects the mental health of mothers after giving birth.
Pendahuluan: Air susu ibu (ASI) adalah makanan atau nutrisi yang terbaik untuk bayi yang merupakan emulsi lemak dalam larutan protein. Perawatan payudara dalam persiapan laktasi adalah salah satu bagian penting yang harus diperhatikan sebagai persiapan untuk menyusui nantinya. Dampak negatif dapat timbul jika tidak dilakukan perawatan payudara sedini mungkin, meliputi : puting susu terpendam, anak susah menyusui, ASI lama keluar, produksi ASI terbatas, pembengkakan payudara, payudara meradang, payudara kotor, ibu belum siap menyusui, kulit payudara terutama puting akan mudah lecet. Metode: Metode yang digunakan dalam program pengabdian masyarakat ini adalah dengan memberikan peningkatan pengetahuan tentang pentingnya perawatan payudara dalam persiapan pemberian ASI. Hasil: Hasil kegiatan tersebut didapatkan peningkatan pengetahuan mengenai pentingnya perawatan payudara dalam persiapan pemberian ASI. Kesimpulan: Pendampingan dan edukasi terkait pelayanan kesehatan khususnya perawatan payudara untuk keberhasilan menyusui adalah hal penting yang harus diketahui ibu hamil
Nyeri pada persalinan umumnya terasa hebat, hanya 2-4% ibu saja yang mengalami nyeri ringan selama persalinan. Nyeri pada saat persalinan menempati skor 30-40 dari 50 skor yang ditetapkan oleh Wall dan Mellzack. Nyeri pada persalinan dapat dikurangi dengan menggunakan metode farmakologi dan nonfarmakologi Salah satu metode untuk mengurangi nyeri persalinan yang sering dilakukan adalah pijat. Salah satu jenis pijat adalah efflurage massage yaitu suatu gerakan dengan mempergunakan seluruh permukaan tangan melekat pada bagian-bagian tubuh yang digosok dengan ringan dan menenangkan.Tujuan penelitian untuk mengetahui pengaruh massage effleurage terhadap tingkat nyeri ibu bersalin kala I fase aktif di kamar bersalin rumah sakit pupuk kaltim tahun 2021. Metode Penelitian ini merupakan Quasi Eksperimen dengan bentuk Nonquivalent Control Group Design, menggunakan total sample dengan jumlah sample 52 responden. Data yang digunakan dalam penelitian ini adalah data primer yaitu data yang didapatkan langsung dari responden melalui pengukuran tentang rasa nyeri yang dirasakan oleh responden. Analisis menggunakan uji Wilcoxon. Hasil penelitian diketahui Asymp.Sig (2-tailed) bernilai <0.001. Karena nilai 0.001<0.05, maka dapat disimpulkan bahwa ada pengaruh massage effleurage terhadap tingkat nyeri pada ibu bersalin. Saran untuk para tenaga kesehatan agar. Massage Effleurage dapat dilakukan sebagai salah satu metode untuk mengurangi tingkat nyeri ibu bersalin kala I fase aktif.
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