The
solubility of 2-mercapto-1,3,4-thiadiazol (MTD) in four kinds
of aqueous mixed solvents including water + (methanol, ethanol, n-propanol, and acetone) was measured by the static gravimetric
method in a temperature range of 278.15–323.15 K. The solubility
of MTD in all selected aqueous mixed solvents was positively correlated
with temperature. The solubility of MTD in the water + acetone solvent
is higher than that in the other three solvents. There is a cosolvency
phenomenon in the solvent systems of water + n-propanol
and water + acetone. The polarity of good solvents plays an important
role in the solubility of MTD in mixed solvents. Three thermodynamic
models including the modified Jouyban–Acree model, NRTL model,
and Wilson model were chosen to correlate the experimental data of
MTD. The NRTL model fits the solubility data of MTD best among all
of the selected thermodynamic models (with RAD = 0.0104, RMSD = 0.000432).
The results demonstrate that all of the models can fit the experimental
data well.
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