Expanding the theoretical knowledge of medical anthropology in the modern field of dental services is one of the main drivers of progress in the orthodontic field. The only way to successfully develop the relationship of these disciplines is to create and fill a database of normative data and search for correlations between various, both obviously related and, at first glance, completely unrelated structures of the human body. The purpose of the study was to determine the features of the relationship between the linear dimensions of molars with the cephalometric parameters of practically healthy men of the first mature age, residents of the western region of Ukraine. Cone-beam computed tomography was performed in 36 practically healthy men of the first mature age, residents of the western region of Ukraine (from Rivne, Volyn, Chernivtsi, Lviv, Ternopil, Khmelnytsky, Ivano-Frankivsk and Zakarpattia regions) followed by odontometry research and cephalometry. Statistical processing of the results was performed in the license package “Statistica 6.1” using non-parametric Spearman’s statistics. As a result of quantitative analysis of reliable and average strength of unreliable correlations of linear computed tomographic sizes of molars with cephalometric indicators and indices of practically healthy men of the western region of Ukraine it is established that the percentage, mainly direct, reliable and average strength of unreliable correlations of linear sizes of molars with cephalometric indices and with indicators of the cerebral or facial skull is almost no different. The largest number of reliable and medium-strength unreliable correlations of linear molars sizes with cranial indices was found with vestibular-lingual and mesio-distal tooth sizes (20.5% with upper molars and 25.0% with lower molars). The highest number of reliable and medium-strength unreliable correlations of linear molars sizes with facial skull indices was found for upper molars with tooth height, crowns and root length (10.8%) and vestibular-lingual and mesio-distal dimensions (12.8%), and for lower molars – only with vestibular-lingual and mesio-distal dimensions (19.4%). The obtained data testify to the prospects of the chosen scientific direction of research, which will further improve the work of physicians in various fields of medicine, including preventive.
Cystatin C improves the risk stratification among people with diabetic nephropathy, the risk of mortality, cardiovascular disease, disorders of the visual organ and nervous system in the preclinical and early stages. The aim of the study was to study the frequency of angio-, retino- and neuropathy, as well as differences in general clinical and anthropometric parameters in patients with type 1 diabetes (T1D) with different levels of albumin in the urine depending on cystatin C. The sample was 78 men and 62 women aged 22-26 years, patients with T1D, who were hospitalized in the therapeutic department №1 and №2 of the Vinnytsia Regional Highly Specialized Endocrinology Center. The control group consisted of 8 healthy men and 13 healthy women of the same age. The level of microalbuminuria and cystatin C was determined for all patients by enzyme-linked immunosorbent assay. The frequency of angio-, retino- and neuropathy, general clinical (systolic, diastolic, pulse) and anthropometric (height, weight, body surface area, waist circumference, body mass index) was assessed indicators. Statistical processing of the obtained results was performed in the license package “Statistica 5.5”, using non-parametric evaluation methods. It was found that in the group of men with cystatin C<0.9, and in women with cystatin C>0.9 with increasing albuminuria, the percentage of patients with more severe microvascular complications of T1D. In patients with diabetes mellitus 1 compared with the control group systolic blood pressure is significantly higher and increases with increasing albumin levels in the urine (with cystatin C<0.9 – in men with normo-, microalbuminuria and proteinuria by 7.14%, 8.1% and 10.8%; in women with normo-, microalbuminuria by 7.5% and 10.0%, with cystatin C>0.9 – in men with normo-, microalbuminuria by 4.9% and 7.2%, in women with proteinuria by 19.5%). Similar changes were found for diastolic blood pressure (with cystatin C<0.9 – in men with proteinuria by 13.0%; in women with normo-, microalbuminuria by 11.4% and 13.4%; with cystatin C>0.9 – in men with microalbuminuria by 9.0%; in women with normo- and proteinuria by 9.5% and 21.5%) and heart rate (with cystatin C<0.9 – in men with microalbuminuria and proteinuria by 18.4% and 12.6%, in women with microalbuminuria by 9.13%; with cystatin C>0.9 – in men with microalbuminuria by 12.0%, in women with normo-, microalbuminuria and proteinuria by 10.1%, 16.3% and 25.3%). In patients with T1D compared to the control group, the length of the body is significantly smaller and decreases with increasing levels of albumin in the urine (with cystatin C<0.9 – in men with normo-, microalbuminuria and proteinuria by 3.6%, 6.7% and 9.0%; women with microalbuminuria by 1.9%, with cystatin C>0.9 – in men with normo-, microalbuminuria by 5.2% and 7.3%, in women with normoalbuminuria and proteinuria by 2.6% and 4.3%). Similar changes were found in men for body weight (with cystatin C<0.9 – with microalbuminuria and proteinuria by 13.6% and 30.1%; with cystatin C>0.9 – with normo- and microalbuminuria by 10.2% and 25.4%) and body surface area (with cystatin C<0.9 – with normo-, microalbuminuria and proteinuria by 5.8%, 10.8% and 18.9%; with cystatin C>0.9 – with normo- and microalbuminuria by 8.2% and 16.2%). The size of the waist circumference in patients with T1D with normoalbuminuria is significantly higher, and in patients of other groups significantly less than in healthy subjects (with cystatin C<0.9 – with normo-, microalbuminuria and proteinuria by 3.8%, 1.2% and 5.2%; cystatin C>0.9 – with microalbuminuria by 5.1%). Compared to healthy women, the waist circumference was significantly higher in sick women (with cystatin C<0.9 – with normo- and microalbuminuria by 11.2% and 10.7%; with cystatin C>0.9 – with normo- and proteinuria by 9.7% and 6.0%). In patients with T1D men with proteinuria compared with the control group, the value of the body mass index was significantly lower by 9.7% (cystatin C<0.9). The value of the body mass index was significantly higher in patients with normoalbuminuria and microalbuminuria – by 11.8% and 17.7% (cystatin C<0.9), respectively, and in patients with proteinuria by 7.2% (cystatin C>0.9) compared with healthy women. Thus, between healthy and patients with T1D with varying degrees of albuminuria, differences in general clinical and anthropometric parameters were found, and they are greater the higher the level of cystatin C.
Annotation. The aim of the study was to examine the differences in lipid, carbohydrate metabolism and renal function in patients with type 1 diabetes (T1D) with different levels of albumin in the urine depending on the level of cystatin C. The sample was 78 men and 62 women aged 22-26 years, T1D patients. The control group consisted of 8 almost healthy men and 13 almost healthy women of the same age. The level of microalbuminuria and cystatin C was determined in all patients by enzyme-linked immunosorbent assay. Biochemical evaluation of fasting glucose, fasting blood glucose, glucose 2 h after exercise, mean value of glucose, glycated hemoglobin, total cholesterol, triglycerides, GFR according to Cockcroft-Gault, CKD EPI and GFR according to cystatin C. Statistical processing of the obtained results was performed in the license package “Statistica 5.5”, using non-parametric evaluation methods. In T1D patients compared to the control group found significantly higher values – fasting blood glucose, glucose 2 hours after exercise, the average value of glucose, glycated hemoglobin, total cholesterol and triglycerides, cystatin C and lower values – international normal ratio, GFR according to Cockcroft-Gault, GFR by CKD EPI and GFR by cystatin C. With increasing levels of albumin in urine in patients with cystatin C<0.9, there were changes in the following indicators: higher values of total cholesterol in men with proteinuria compared to men with normo- and microalbumin ; and lower values – the international normal ratio in women with microalbuminuria, compared with women with normoalbuminuria; Cockcroft-Gault GFR in men with proteinuria and GFR by CKD EPI in men with proteinuria and microalbuminuria compared to men with normoalbuminuria. With increasing levels of albumin in the urine in patients with cystatin C>0.9 there were changes in the level of the following indicators: higher values – fasting blood glucose and triglycerides in women with proteinuria compared with women with normoalbuminuria, and glycated hemoglobin and total cholesterol compared with and microalbuminuria; international normal ratio in men with microalbuminuria, compared with men with normoalbuminuria; and smaller values – GFR level by Cockcroft-Gault in men with microalbuminuria compared to men with normoalbuminuria; GCF levels by Cockcroft-Gault in women with proteinuria compared to women with microalbuminuria and GFR levels by CKD EPI in women with proteinuria compared to women with normoalbuminuria and microalbuminuria. With increasing levels of cystatin C, a decrease in glycated hemoglobin in men and women with microalbuminuria and triglycerides in women with microalbuminuria, as well as greater values of the international normal ratio in men with normoalbuminuria and GFR on cystatin C in men and women with normoalbuminuria and micro. Thus, the study obtained results that indicate the existence of differences in the studied indicators between healthy and sick subjects, between men and women and between groups of T1D patients’ men or women with different levels of albumin and cystatin C.
Паутина: высокоскоростная коммуникационная сеть Аннотация. В статье представлена разработанная в Институте программных систем им. А.К. Айламазяна РАН в кооперации с отечественными компаниями высокоскоростная коммуникационная сеть Паутина, основанная на активных оптических кабелях (АОК) и программируемых логических интегральных схемах (ПЛИС). Данная сеть предназначена для использования в высокопроизводительных вычислительных системах (суперкомпьютерах). В рамках проекта разработана плата сетевого адаптера, активные оптические кабели, а также аппаратное (на основе ПЛИС) и программное обеспечение. Технические характеристики сети находятся на современном уровне и обеспечивают скорость передачи данных до 56 Гбит/с между двумя платами по активному оптическому кабелю. Ключевые слова и фразы: коммуникационная сеть, активный оптический кабель, ПЛИС, высокопроизводительная вычислительная система, суперкомпьютер. Введение Современные высокопроизводительные вычисления невозможны без быстрых вычислительных устройств (процессоров, ускорителей вычислений) и быстрых подсистем передачи данных (как в рамках одного вычислительного узла между вычислительными устройствами и памятью, так и между вычислительными узлами). Во многих приложениях именно коммуникационные сети, связывающие узлы суперкомпьютеров, являются наиболее узким местом. Наиболее распространенная и доступная на текущий момент коммуникационная сеть-InfiniBand FDR, обладающая высокими характеристиками: скоростью передачи данных 56 Гбит/с на линк. Однако Работа выполнена в рамках государственного контракта с Министерством промышленности и торговли Российской Федерации № 12411.1006899.11.105.
Burnout-syndrome is a state of physical, motivational and, above all, emotional exhaustion, which is characterized by impaired productivity/education, the presence of severe fatigue, insomnia and increased susceptibility to the formation of somatic diseases, as well as the use of psychoactive substances, in order to obtain temporary relief, which has a pronounced tendency to develop psychological or physiological dependence and the formation of suicidal behavior. The purpose of the work is to determine the leading indicators of emotional burnout of pupils aged 15-17 years and to establish the features of their dynamic changes during education in a modern school. The research using Boyko's personal questionnaire was conducted on the basis of a number of secondary schools located in Vinnytsia, during which 309 pupils (158 young women and 151 young men) at the age of 15-17 years old were supervised. The analysis of the obtained data involved the application of descriptive statistics procedures based on the use of the standard package of statistical analysis applications “Statistica 6.1” (licensed № AXX910A374605FA). The obtained data testify to the fact that the syndrome of emotional burnout is most often observed among pupils at the aged 15 and 17, and in terms of age and sex, mainly among young men compared to young women. The differences between the rates of young women and young men are probably to be explained by their greater emotional openness and greater resistance of the organism to the action of stressors in comparison with young men. On the other hand, high levels of emotional burnout among young men compared to young women testify to their inability to spend their emotions economically, to effectively resist the actions of traumatic environmental factors and social living conditions. It is determined that the level of emotional burnout of schoolchildren is high among young women – due to the high level of expression of the phase of resistance, which indicates the development of resistance to emotional stress, among young men – due to phases of stress and exhaustion, which indicates significant depletion of adaptation mechanisms. The identified trends determine the need to develop conceptual frameworks for overcoming the leading manifestations of emotional burnout, which involve the use of personality-oriented approaches to improve the individual's ability to cope with stress due to changing stereotypes of their own behavior, relationships and relationships with others. mastering stress management skills, learning relaxation techniques, introduction of psychohygienic correction measures to pupils’ daily activities.
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