Objective:
During use, contact lens disinfecting solutions are exposed to tears and clinical microbial isolates. The current study was designed to test the performance of several disinfecting solution in the presence of organic soils or clinical isolates.
Methods:
Standard and clinical isolates were exposed to the disinfecting solutions in the presence or absence of different organic soils. The number of microbial cells killed during disinfection was established by growing cells after disinfection on agar plates.
Results:
The disinfecting activity of the povidone-iodine or hydrogen peroxide solutions was not affected by the organic soils or clinical isolates. The presence of yeast organic soil did not affect the performance of the disinfecting solutions when tested with standard microbial strains, but the addition of a model tear organic soil significantly reduced the disinfecting activity of the solutions containing various combinations of polyhexamethylene biguanide, polyquaternium-1, alexidine, and myristamindopropyl dimethylamine especially when tested against the standard fungal strains (reducing the effectiveness by between 0.5–4 log10) or the clinical bacterial isolates (reducing the effectiveness by between 0.5–3.5 log10). One disinfecting solution that contained polyquaternium-1 and myristamindopropyl dimethylamine had very poor activity against the clinical bacterial isolates in the absence or presence of either organic soil.
Conclusions:
Povidone-iodine or hydrogen peroxide disinfecting solutions are not affected by organic soils and are very active against clinical bacterial isolates. Disinfecting solutions containing combinations of polyhexamethylene biguanide, polyquaternium-1, alexidine, and myristamindopropyl dimethylamine are affected by model tear organic soil and may have poor activity against clinical isolates.
Technologies for processing inorganic compounds into high-definition products are used in many areas including thin-film transistors and liquid crystal displays. These technologies are based on the technology of depositing thin films of 1 μm or less in thickness using vacuum processes such as sputtering and vapor deposition. The present review compiles the results of research made on photosensitive paste technology for processing inorganic materials into high-definition thick films of several micrometers to less than 200 micrometers in thickness. The technology for processing inorganic materials into films of several micrometers to less than 200 micrometers in thickness is used for producing the electrodes and barrier ribs of plasma display panel (PDP), and is expected to widely spread into such areas as IC packages in the future.
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