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A 37-year-old man developed encephalopathy with prominent eosinophilia. Magnetic resonance imaging (MRI) revealed multiple T2-weighted high signal intensity lesions with dimeglumine gadopentetate (Gd-DTPA) enhancement on Tl-weighted images, which were distributed in the cerebral cortex, thalamus, deep white matter and cerebellum. He was diagnosed as having systemic mastocytosis on the basis ofproliferating mast cells in the bone marrowand peripheral eosinophilia. Following steroid administration, there was a rapid improvementof his symptomsand laboratory data. To our knowledge, this was the first reported case of systemic mastocytosis provoking encephalopathy with serial MRIfindings. (Internal Medicine 33: 23-26, 1994)

Subacute combined degeneration (SCD) of the spinal cord is well known to produce degenerative lesions in the spinal cord histopathologically, but a few reports on the neuroradiological findings have so far been reported. We presented the MRI findings of the spinal cord in a case of SCD. The localization of the radiologically proven lesions was similar to that of the previous pathological reports.

No abstract