S evere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of the current rapidly growing outbreak of coronavirus disease (COVID-19), originating from the city of Wuhan, Hubei Province, China (1). Initially, 41 cases of "pneumonia of unknown etiology" were reported to the World Health Organization by the Wuhan Municipal Health Committee at the end of December 2019 (2). On January 8, 2020, the pathogen was identified (1), and human-to-human transmission was reported soon after. By January 21, most provinces of China had reported COVID-19 cases. By March 16, the outbreak had led to >170,000 total confirmed cases and >6,500 deaths globally. In a period of 3 months, an outbreak of apparent idiopathic pneumonia had become the COVID-19 pandemic.Studying dynamics of a newly emerged and rapidly growing infectious disease outbreak, such as COVID-19, is important but challenging because

In a six-year program started in July 2014, the Extended Baryon Oscillation Spectroscopic Survey (eBOSS) will conduct novel cosmological observations using the BOSS spectrograph at Apache Point Observatory. These observations will be conducted simultaneously with the Time Domain Spectroscopic Survey (TDSS) designed for variability studies and the Spectroscopic Identification of eROSITA Sources (SPIDERS) program designed for studies of X-ray sources. In particular, eBOSS will measure with percent-level precision the distance-redshift relation with baryon acoustic oscillations (BAO) in the clustering of matter. eBOSS will use four different tracers of the underlying matter density field to vastly expand the volume covered by BOSS and map the large-scale-structures over the relatively unconstrained redshift range 0.6 < z < 2.2. Using more than 250,000 new, spectroscopically confirmed luminous red galaxies at a median redshift z = 0.72, we project that eBOSS will yield measurements of the angular diameter distance d A (z) to an accuracy of 1.2% and measurements of H(z) to 2.1% when combined with the z > 0.6 sample of BOSS galaxies. With ∼ 195, 000 new emission line galaxy redshifts, we expect BAO measurements of d A (z) to an accuracy of 3.1% and H(z) to 4.7% at an effective redshift of z = 0.87. A sample of more than 500,000 spectroscopically-confirmed quasars will provide the first BAO distance measurements over the redshift range 0.9 < z < 2.2, with expected precision of 2.8% and 4.2% on d A (z) and H(z), respectively. Finally, with 60,000 new quasars and reobservation of 60,000 BOSS quasars, we will obtain new Lyα forest measurements at redshifts z > 2.1; these new data will enhance the precision of d A (z) and H(z) at z > 2.1 by a factor of 1.44 relative to BOSS. Furthermore, eBOSS will provide improved tests of General Relativity on cosmological scales through redshift-space distortion (RSD) measurements, improved tests for non-Gaussianity in the primordial density field, and new constraints on the summed mass of all neutrino species. Here, we provide an overview of the cosmological goals, spectroscopic target sample, demonstration of spectral quality from early data, and projected cosmological constraints from eBOSS. eBOSS 3 confidence, where w is the ratio of pressure to energy density for dark energy. Thus, current observations are generally consistent with the simplest picture where dark energy is described completely by Einstein's cosmological constant (Λ).New precise observations can unravel the origin of the accelerating universe; specifically, to determine if cosmic acceleration is caused by deviations in General Relativity (GR) on large scales or by a new form of (dark) energy. It is possible to decouple scenarios of acceleration that require dark energy from those that require modifications to GR by independently probing both cosmic expansion history and the structure growth rate. Four primary observational techniques are generally accepted as the most powerful toward obtaining that goal (e.g. Albrech...

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We calculate the real-and redshift-space clustering of massive galaxies at z ∼ 0.5 using the first semester of data by the Baryon Oscillation Spectroscopic Survey (BOSS). We study the correlation functions of a sample of 44,000 massive galaxies in the redshift range 0.4 < z < 0.7. We present a halo-occupation distribution modeling of the clustering results and discuss the implications for the manner in which massive galaxies at z ∼ 0.5 occupy dark matter halos. The majority of our galaxies are central galaxies living in halos of mass 10 13 h −1 M ⊙ , but 10% are satellites living in halos 10 times more massive. These results are broadly in agreement with earlier investigations of massive galaxies at z ∼ 0.5. The inferred large-scale bias (b ≃ 2) and relatively high number density (n = 3 × 10 −4 h 3 Mpc −3 ) imply that BOSS galaxies are excellent tracers of large-scale structure, suggesting BOSS will enable a wide range of investigations on the distance scale, the growth of large-scale structure, massive galaxy evolution and other topics. Subject headings: cosmology: large-scale structure of universe

We present constraints on cosmological and astrophysical parameters from high-resolution microwave background maps at 148 GHz and 218 GHz made by the Atacama Cosmology Telescope (ACT) in three seasons of observations from 2008 to 2010. A model of primary cosmological and secondary foreground parameters is fit to the map power spectra and lensing deflection power spectrum, including contributions from both the thermal Sunyaev-Zeldovich (tSZ) effect and the kinematic Sunyaev-Zeldovich (kSZ) effect, Poisson and correlated anisotropy from unresolved infrared sources, radio sources, and the correlation between the tSZ effect and infrared sources. The power ℓ 2 C ℓ /2π of the thermal SZ power spectrum at 148 GHz is measured to be 3.4 ± 1.4 µK 2 at ℓ = 3000, while the corresponding amplitude of the kinematic SZ power spectrum has a 95% confidence level upper limit of 8.6 µK 2. Combining ACT power spectra with the WMAP 7-year temperature and polarization power spectra, we find excellent consistency with the LCDM model. We constrain the number of effective relativistic degrees of freedom in the early universe to be N eff = 2.79 ± 0.56, in agreement with the canonical value of N eff = 3.046 for three massless neutrinos. We constrain the sum of the neutrino masses to be Σm ν < 0.39 eV at 95% confidence when combining ACT and WMAP 7-year data with BAO and Hubble constant measurements. We constrain the amount of primordial helium to be Y p = 0.225 ± 0.034, and measure no variation in the fine structure constant α since recombination, with α/α 0 = 1.004 ± 0.005. We also find no evidence for any running of the scalar spectral index, dn s /d ln k = −0.004 ± 0.012.

We report on 23 clusters detected blindly as Sunyaev-Zel'dovich (SZ) decrements in a 148 GHz, 455 deg 2 map of the southern sky made with data from the Atacama Cosmology Telescope 2008 observing season. All SZ detections announced in this work have confirmed optical counterparts. Ten of the clusters are new discoveries. One newly discovered cluster, ACT-CL J0102−4915, with a redshift of 0.75 (photometric), has an SZ decrement comparable to the most massive systems at lower redshifts. Simulations of the cluster recovery method reproduce the sample purity measured by optical follow-up. In particular, for clusters detected with a signal-to-noise ratio greater than six, simulations are consistent with optical follow-up that demonstrated this subsample is 100% pure. The simulations further imply that the total sample is 80% complete for clusters with mass in excess of 6 × 10 14 solar masses referenced to the cluster volume characterized by 500 times the critical density. The Compton y-X-ray luminosity mass comparison for the 11 best-detected clusters visually agrees with both self-similar and non-adiabatic, simulation-derived scaling laws.

Using high-resolution microwave sky maps made by the Atacama Cosmology Telescope, we for the first time present strong evidence for motions of galaxy clusters and groups via microwave background temperature distortions due to the kinematic Sunyaev-Zel'dovich effect. Galaxy clusters are identified by their constituent luminous galaxies observed by the Baryon Oscillation Spectroscopic Survey, part of the Sloan Digital Sky Survey III. We measure the mean pairwise momentum of clusters, with a probability of the signal being due to random errors of 0.002, and the signal is consistent with the growth of cosmic structure in the standard model of cosmology.

124 Main text including references and figure captions: 3,945 All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity. AbstractThe novel coronavirus (2019-nCoV) is a recently emerged human pathogen that has spread widely since January 2020. Initially, the basic reproductive number, R0, was estimated to be 2.2 to 2.7. Here we provide a new estimate of this quantity. We collected extensive individual case reports and estimated key epidemiology parameters, including the incubation period. Integrating these estimates and high-resolution real-time human travel and infection data with mathematical models, we estimated that the number of infected individuals during early epidemic double every 2.4 days, and the R0 value is likely to be between 4.7 and 6.6. We further show that quarantine and contact tracing of symptomatic individuals alone may not be effective and early, strong control measures are needed to stop transmission of the virus.