Derivatives of hexahydro-8-isoquinolone with electron-acceptor substituents (nitro or ethylthiocarbonyl groups) in position 4 represent a group of compounds that have not been investigated adequately, namely hydrogenated nitrogen heterosystems containing a/3-aminovinylcarbonyl structural fragment in which the keto group is f'Lxed in the s-cis-configuration with respect to the double bond. In the work reported here, we synthesized and studied new representatives of this class of compounds. In the electronic spectra of compounds IIIa,b,c, which were synthesized here for the first time, there are long-wave absorption bands with maxima at 455, 448, and 421 nm, respectively ( Table 1) -bands that are characteristic for compounds of the hexahydroisoquinolone series [2]. In the spectra of compound IIIc, we found a 23-nm bathochromic shift of the longwave maximum relative to the oxygen-containing analog, indicating a stronger conjugation of the ethylthiocarbonyl substituent with the/3-aminovinyl system [2, 4].
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.