Ethyl esters of 1,4-dihydropyridine-3,5-dicarbothionic acids

Identification of dihydropyridines that reduce cellular tau levels

“…To expand the diversity in this collection, we took advantage of published methods 8 to exchange the ester for a thioester on compounds 4a and 4b . Briefly, these examples were refluxed in toluene with 2.2 equivalents of Lawesson's reagent for 1 hr.…”