Synthesis of phenyl-substituted derivatives of decahydrophenanthridine-1, 7-dione and hexahydro-8-isoquinolone

Synthesis and using of 10-hydroxy-3,3,6,6-tetramethyl-9-(4-hydroxy-3-methoxyphenyl)-1,2,3,4,5,6,7,8,9,10-decahydroacridin-1,8-dion as acid base titration indicator

“…Heterocyclic compounds that include the 1,4-dihydropyridine fragment in their structure are of great interest to medical chemists [1][2][3] due to their wide range of biological effects. Compounds of this type have antihypertensive, anticonvulsant, antioxidant antibacterial, antiviral, antiviral, spasmolytic, contraceptive activity, without showing a mutagenic effect [4][5][6].…”

Synthesis of Tri- and Tetracycle Compounds via Reaction of 1,3-Decalinediones and 4-Hydroxycoumarines with 2-Acetyl-2-Cyclohexenes and Biological Testing

“…Dehydration of bicycles (6 a, b, c) in the presence of acid leads to the formation of pyran ring with the formation of tricycles (7a, b). Interaction of ketodienols with β-enaminones gives new derivatives hexahydroisoquinoline (8a, b, c) and decahydrophenanthridine (7d, e) [13] [14]. It should be noted that currently it has been revealed that there is an effective way to obtain not only acetylcyclohexenone (3b) [15], but also acetylcyclopentenenone (3a) [16] and other related endions [17]- [19] from corresponding cis-β-diketones by their selenenylation followed by selenoxide elimination of with hydrogen peroxide.…”