Purpose: To analyse the relationship between lower gastrointestinal symptoms and clinicopathological features in colorectal polyp patients.
Methods: We retrospectively collected the clinicopathological information of outpatients undergoing colonoscopy atLuhe Hospital Affiliated with Capital Medical University.
We performed tendency score matching (PSM) between colorectal polyp patients and polyp-free patients by age and sexat a ratio of 1:1 andthen analysed the relationships between colorectal polyps and clinical symptoms by univariate and multivariate analyses.
Results: 1) This study included 2483 patients with colorectal polyps and 2483 polyp-free patients. 2) The proportion of abdominal distension and haematochezia was increased in patients with colorectal polyps (25.6% vs. 22.9%, P = 0.024; 21.5% vs. 16.8%, P = 3.4E-5), but the proportion of diarrhoea wasdecreased (35.1% vs. 37.9%, P = 0.036). 3) Patients with haematochezia usually hadlarger polyp sizes [univariate p= 0.014; multivariate 95% CI1.034 (1.001, 1.069), p = 0.043]. 4) Patients with diarrhoea typically had a smaller polyp size [univariate p = 0.078; multivariate 95% CI0.971(0.944, 0.999), p = 0.043]. 5) Constipation and other symptoms had little correlation with the clinicopathological features of colorectal polyps.
Conclusions: Haematochezia is positively correlated with the presence and size of colorectal polyps, and diarrhoea is negatively correlated with the presence and size of colorectal polyps.
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