B1LHARZ1AS1S*, or schistosomiasis, is a trematode worm infestation of man. It is estimated, according to the last W.H.O. reports, that 200 million people are infested with it in different parts of the world. Three species of these worms are prevalent in Africa, South America, the Middle East and SouthEast Asia; hematobium, mansoni and japonicum. Although the main habitat of these worms is in the liver, the portal circulation and in the prostatic and visical plexuses of veins, ectopic forms of schistosomiasis are described in many other locations, the chest, skin, eye and the central nervous system. * The term Bilharziasis refers to Dr Theodore Bilharz, the German physician who first discovered the schistosoma worms.

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The effect of six antidepressants has been investigated in six groups of twenty patients suffering from depressive states. The over-all response of the six groups, as well as the response of the individual target symptoms of depression according to the Hamilton Rating Scale are reported.

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