Living related liver transplantation in Egypt: an emerging program

El-Meteini, Mahmoud; Fayez, Alaaeldin; Fathy, Mohamed; Abdalaal, Amr; Safaan, H; Mostafa, Ibrahim; Abdalaal, Mohamed; Syam, Mohammad; Refay, R; Abou-Alfetouh, F; Khedr, Hisham; El-Halafawy, Yasser Mohamed; Taher, Y; Abdelrahman, Hams; Badawy, S. H.; Ryad, A; Awad, H.; Abdallah, Ahmed; Ghafar, Tharwat Abdul; El-Monayeri, Magda; Hoballah, Aly; Eldorry, Ahmed; Adham, Mustapha; Boillot, Olivier

doi:10.1016/j.transproceed.2003.09.052

Cited by 12 publications

(16 citation statements)

References 11 publications

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“…The first living-donor liver transplantation (LDLT) in Egypt was performed in 2001 [6]. Since then, many centers have adopted this procedure as the only transplantation modality in patients with end-stage liver disease.…”

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confidence: 99%

Infection Complications and Pattern of Bacterial Resistance in Living-Donor Liver Transplantation: A Multicenter Epidemiologic Study in Egypt

Mukhtar

Abdelaal

Hussein

et al. 2014

Transplantation Proceedings

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confidence: 99%

Infection Complications and Pattern of Bacterial Resistance in Living-Donor Liver Transplantation: A Multicenter Epidemiologic Study in Egypt

Mukhtar

Abdelaal

Hussein

et al. 2014

Transplantation Proceedings

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“…5 Shorter waiting lists, good quality of organs, avoidance of the need to search for suitable living related donors, and avoidance of exposure of a loved one to the risk of a major operation are additional factors contributing to Egyptian patients who can afford the costs seeking cadaveric LT in Eastern countries. [8][9][10] El-Gazzaz and El-Elemi Dovepress submit your manuscript | www.dovepress.com…”

Section: Discussionmentioning

confidence: 99%

“…During the same period, the number of patients who underwent living related LT in Egypt are getting small as most of the centers did less number of patients during the last year than previous years, [3][4][5][6][7][8] and this also raises concerns regarding the negative impact of LT in China on the growing LDLT program in Egypt and on the volume of cases done every year in these centers.…”

Section: Dovepressmentioning

confidence: 99%

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Liver transplantation in Egypt from West to East

El-Gazzaz

El-Elemi²

2010

TRRM

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Background: Egyptian patients with end-stage liver disease need to seek whole cadaveric liver transplantation (CLT) abroad. We studied the outcome of Egyptian patients who underwent CLT in China. Methods: Between 2004Between -2006 patients who underwent CLT in China and attended two liver surgery outpatient clinics in Egypt for follow-up were included in the study. Demographic, preoperative, postoperative, and follow-up data after coming back from China were reviewed. Results: For 22 patients of median age 48 years (30-62) and with BMI 27.5 ± 6.2, the median follow-up was 23.5 months (range 1-48); 18 patients were males. Hepatitis C (HCV)-cirrhosis alone or with schistosomiasis was the main indication for CLT (n = 12); Hepatitis B (HBV)-cirrhosis was the indication for transplantation in two patients, HCV-cirrhosis with hepatocellular carcinoma (HCC) in six, HBV-cirrhosis with HCC in one, and both HBV-and HCV-related cirrhosis with HCC in another. There were eight deaths, one as a result of primary nonfunction, one because of postoperative bleeding, two because of recurrent HCV, and four because of recurrent HCC. Overall survival at one and three years was 68.5% and 64%, respectively, and 50% and 37.5% for HCC patients, respectively, while three-year survival was 80% for hepatitis patients. Twelve patients (54%) developed complications. Biliary complications occurred in 45% of cases. Conclusion: CLT tourism to China raises serious concerns regarding selection criteria and ethical issues. Furthermore, the negative impact of this practice on the successful setting up of LT programs in Egypt must be addressed carefully. In Egypt efforts should be directed to get legalization for CLT.

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“…Accepted criteria of live donation were met within a family member in 144 (69.6%) donors whereas the remaining 63 (30.4%) cases could not identify a reasonable sibling for donation and received a RLG from an unrelated friend. The three‐steps donor preparation protocol has been reported elsewhere 2 . Liver biopsy is a routine practice in donor preparation and macrovesicular steatosis is only accepted if it is between 0 and 15% with the total absence of any portal inflammation.…”

Section: Methodsmentioning

confidence: 99%