Bilharzial granuloma of the conus medullaris and cauda equina

El-Banhawy, Ahmed; Elwan, Osamah; Taher, Y

doi:10.1038/sc.1972.29

Cited by 17 publications

(16 citation statements)

References 9 publications

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“…A current revision of the Brazilian and international literature, by Index-Medicus and Latin-American Index-Medicus, found 50 cases of SCS in children 7,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] and the adult patients series by Galvão 11 and Peregrino et al 26 were compared with the authors' findings.…”

Section: Methodsmentioning

confidence: 99%

Spinal cord schistosomiasis in children: analysis of seven cases

Paz

Valente

Casella

et al. 2002

Arq. Neuro-Psiquiatr.

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-We describe seven cases of children (ages 2 to 14 years) with myeloradiculopathy caused by infection with S. mansoni. None of them presented hepatosplenic involvement and one presented an intestinal picture. The myeloradicular and pseudotumoral forms were observed in four and three patients, respectively. Comparing the reports in the literature, we found that the pseudotumoral form is more similary frequent among children than in adults, while the myelitic and myeloradicular forms are the most frequent and distributed across all age groups. Diagnosis is based on clinical and epidemiological findings in association with laboratory tests. The diagnosis was confirmed by the presence of S. mansoni eggs in feces (5 cases) and / or the positivity in specific immunological tests (5 cases) associated with a cerebrospinal fluid inflammatory pattern with presence of eosinophils (between 1 and 24%). Magnetic resonance image, although it does not enable an etiological diagnosis, helped to confirm the form and spinal cord level of the lesion.KEY WORDS: schistosoma mansoni, spinal cord schistosomiasis, schistosomal myelopathy, myelitis, spinalcord pseudotumor, child. Esquistossomose medular em crianças: análise de sete casosRESUMO -Relatamos sete crianças com mielorradiculopatia devida a infecção pelo S. mansoni, com idade entre 2 e 14 anos. Nenhuma apresentou acometimento hepatoesplênico e uma apresentou quadro intestinal. A forma mielorradicular foi observada em quatro pacientes e a pseudotumoral em três. Revendo os achados da literatura, encontramos que a forma pseudotumoral é mais frequente nas crianças que nos adultos, apesar das formas mielíticas e mielorradiculares serem ainda as mais frequentes em todas as idades. O diagnóstico baseou-se nos achados clínicos e epidemiológicos, associados aos laboratoriais. A presença de ovos de S. mansoni nas fezes (5 casos) e/ou a positividade de testes imunológicos específicos no liquido cefalorraquidiano (5 casos), com padrão inflamatório e eosinofilorraquia (entre 1 e 24%) confirmou o diagnóstico. O estudo da imagem de ressonância magnética, apesar de não permitir o diagnóstico etiológico, ajudou a confirmar a forma e o nível medular da lesão. PALAVRAS-CHAVE: esquistosomose mansoni, esquistossomose medular, mielopatia esquistossomótica, mielite, pseudotumor medular, criança. . The prevalence of oviposition in the central nervous system (CNS) varies among studies from 0.3 to 30 percent of infected individuals [3][4][5] . It is generally myeloradicular and occasionally encephalitic, as opposed to Schistosomiasis japonica in which encephalitic involvement is more frequent. Many patients remain asymptomatic. Spinal cord schistosomiasis (SCS) is one of the most frequent causes of non-traumatic myelopathies, responsible for 6% of these in endemic areas 6 . Vascular lesions caused by SM appear to be responsible for the neurological sequels. Vascular obstruction in the spinal cord (SC) is secondary to the formation of a granuloma, with an intense inflammatory reaction and ischem...

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Section: Methodsmentioning

confidence: 99%

Spinal cord schistosomiasis in children: analysis of seven cases

Paz

Valente

Casella

et al. 2002

Arq. Neuro-Psiquiatr.

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“…Além disso, a reação imunológica liquórica pode estar ausente mesmo em casos comprovados de MRE 31 .…”

Section: Análise Do Liquorunclassified

Mielorradiculopatia esquistossomótica

Silva

Maciel²,

Ribas³

et al. 2004

Rev. Soc. Bras. Med. Trop.

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“…Unfortunately a reaction even in the cerebrospinal fluid mnay be absent in schistosomal myelopathy.i It is useful to know that oxamniquine (which has been used previously in schistosomal myelopathy9 10) appeared to have been rapidly efficacious in this instance. Any apparent effect must be considered, however, in the context of a condition which has been reported to respond rapidly to many different treatment regimens and which may also spontaneously remit for prolonged periods.7 II Because the condition is so rarely encountered and the pathological findings are so variable it is difficult to compare the results of different treatment regimens.7 12 The cases reported reflect inexperience in the approach to tuberculin testing rather than a fault in the test itself. The tuberculin reaction is generally very strong in the presence of primary tuberculous lesions and may remain so for many years after healing.'…”

Section: Electrocution)mentioning

confidence: 99%

Which patients are likely to die in an accident and emergency department?

Symmers¹

1984

BMJ

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Bilharzial granuloma of the conus medullaris and cauda equina

Cited by 17 publications

References 9 publications

Spinal cord schistosomiasis in children: analysis of seven cases

Spinal cord schistosomiasis in children: analysis of seven cases

Mielorradiculopatia esquistossomótica

Which patients are likely to die in an accident and emergency department?

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