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Conjugated linolenic acid (CLNA) is a mixture of positional and geometric isomers of octadecatrienoic acid (α-linolenic acid, cis9,cis12,cis15-18:3 n-3) found in plant seeds. Three 8,10,12-18:3 isomers and four 9,11,13-18:3 isomers have been reported to occur naturally. CLNA isomers such as punicic acid, α-eleostearic acid and jacaric acid have been attributed to exhibit several health benefits that are largely based on animal and in vitro studies. This review has summarized and updated the evidence regarding the metabolism and bioactivities of CLNA isomers, and comprehensively discussed the recent studies on the effects of anti-carcinogenic, lipid metabolism regulation, anti-inflammatory, anti-obese and antioxidant activities of CLNA isomers. The available results may provide a potential application for CLNA isomers from natural sources, especially edible plant seeds, as effective functional food ingredients and dietary supplements for the above mentioned disease management. Further research, especially human randomized clinical trials, is warranted to investigate the detailed physiological effects, bioactivity and molecular mechanism of CLNA.

Abstract:Chitosan-based active films were developed by incorporation of carvacrol (10 g/L), pomegranate peel extract (PPE, 10 g/L) and carvacrol + PPE (10 g/L of each) and their physical, antioxidant and antimicrobial properties were investigated. Incorporation of carvacrol and carvacrol + PPE into the films significantly decreased the water vapor permeability, tensile strength and percentage of elongation at break. Incorporation of carvacrol, PPE and carvacrol + PPE into the films decreased the transparency, but significantly increased the total phenol content and antioxidant activity. All the films, with the exception of PPE-incorporated film, exhibited antibacterial activity against Escherichia coli and Staphylococcus aureus. In addition, the antibacterial activity against Staphylococcus aureus of the film incorporated with carvacrol + PPE was moderately higher than that incorporated with carvacrol or PPE alone, suggesting a synergistic action between carvacrol and PPE.

Conjugated fatty acids including conjugated linoleic acid (CLA) and conjugated linolenic acid (CLNA) have drawn significant attention for their variety of biologically beneficial effects. Evidence suggested that CLA and CLNA could play physiological roles by regulating the expression and activity of PPAR γ. This review summarizes the current understanding of evidence of the role of CLA (cis-9,trans-11 CLA and trans-10,cis-12 CLA) and CLNA (punicic acid and α-eleostearic acid) in modulating the expression or activity of PPAR γ that could in turn be employed as complementary treatment for obesity and inflammatory bowel disease.

Methoxyphenols emitted from lignin pyrolysis are widely used as potential tracers for biomass burning, especially for wood burning. In the past ten years, their atmospheric reactivity has attracted increasing attention from the academic community. Thus, this work provides an extensive review of the atmospheric reactivity of methoxyphenols, including their gas-phase, particle-phase, and aqueous-phase reactions, as well as secondary organic aerosol (SOA) formation. Emphasis was placed on kinetics, mechanisms, and SOA formation. The reactions of methoxyphenols with OH and NO3 radicals were the predominant degradation pathways, which also had significant SOA formation potentials. The reaction mechanism of methoxyphenols with O3 is the cycloaddition of O3 to the benzene ring or unsaturated CC bond, while H-abstraction and radical adduct formation are the main degradation channels of methoxyphenols by OH and NO3 radicals. Based on the published studies, knowledge gaps were pointed out. Future studies including experimental simulations and theoretical calculations of other representative kinds of methoxyphenols should be systematically carried out under complex pollution conditions. In addition, the ecotoxicity of their degradation products and their contribution to SOA formation from the atmospheric aging of biomass-burning plumes should be seriously assessed.

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This study aimed to elucidate the effect of punicic acid (PUA, cis9,trans11,cis13-18:3) on obesity and liver steatosis in mice induced by high‑fat diet (HFD), and to explore the possible mechanism....

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