Aim: to evaluate anxiety and depression disorders among medical students during COVID-19 pandemic. Methods: cross-sectional study of medical students conducted in May 2020 with questionnaires regarding social and demographic status and GAD-7 for anxiety and PHQ-9 for depression questionnaires. Results: participated 340 (97.98%) students. Average GAD-7 score was 9.18 (M = 9.18; SD = 4.75); average PHQ-9 score was 12.72 (M = 12.72; SD = 6.62). Results indicate a positive significant relationship between GAD-7 and females, and social distancing affecting finances. Using cut-off score of 10 for GAD-7, 157 (46.17%) students were identified with moderated or severe symptoms of anxiety. For PHQ-9 score, using cut-off of 10, 219 (64.41%) students were identified with moderate or severe symptoms of depression; results indicate a positive significant relationship between PHQ-9 and females and between social distancing affecting finances. Conclusion: analysis demonstrated a higher prevalence of moderated and severe anxiety and depression symptoms among medical students during COVID-19 pandemic, significantly among women and on medical students relating financial impairment related to COVID-19 epidemic.

OBJETIVO: Avaliar o estado nutricional e os níveis hematológicos e séricos de ferro em pré-escolares de municípios com diferentes índices de desenvolvimento infantil (IDI). MÉTODOS: Estudo transversal de 34 pré-escolares com idade de três a seis anos do município de Laranjal, Paraná, com IDI baixo e com o mesmo número de crianças pareadas por idade e gênero, provenientes de Presidente Prudente, São Paulo, município com IDI médio. Avaliou-se o estado nutricional por meio do escore Z das relações peso/estatura e estatura/idade. A avaliação bioquímica constou de dosagens de hemoglobina, hematócrito, ferro sérico e ferritina. Para a análise estatística foram usados os testes t de Student, Mann-Whitney, qui-quadrado e o exato de Fisher. RESULTADOS: Peso, estatura e escore Z das relações antropométricas foram significantemente menores no grupo de crianças de Laranjal comparados aos de Presidente Prudente. A prevalência de anemia em ambos os grupos foi 8,8%, não havendo diferença significante para a prevalência de ferropenia e para os valores de ferritina sérica. CONCLUSÕES: Pré-escolares do município com IDI baixo apresentam mais desnutrição, enquanto sobrepeso e obesidade são predominantes nos pré-escolares do município com IDI médio. Quanto às alterações dos níveis hematológicos e séricos de ferro, não há diferença entre os pré-escolares dos municípios estudados.

Background: Emotional disorders in medical students are expected and deserve more attention, especially during the COVID-19 Pandemic. Objective: Evaluate anxiety and depression disorders among medical students during the COVID-19 Pandemic. Methods:  A cross-sectional study at a private medical college in Brazil, two months after stay-at-home order and postponed classes due to the COVID-19 Pandemic. A survey among medical students was conducted in May 2020, using questionnaires regarding social and demographic status, the GAD-7 for symptoms of anxiety, and the PHQ-9 for symptoms of depression. Results: A total of 340 of 347 (97.98%) medical students participated. The average GAD-7 score was 9.18 (±4.75), and the average PHQ-9 score was 12.72 (±6.62). The results indicate a significant positive relationship between GAD-7 and females (F=5.816 P=.016). Using a cut-off score of 10 for GAD-7, 157 (46.17%) students were identified with moderate or severe anxiety symptoms. For the PHQ-9 score, using a cut-off of 10 219 (64.41%), students were recognized with moderate or severe symptoms of depression; the results indicate a significant positive relationship between the PHQ-9 and females (F=5.640 P=.018). Conclusion: The analysis demonstrated a significantly higher prevalence of moderate and severe anxiety    and depression symptoms among female medical students during the COVID-19 Pandemic.

The discovery of the antiretroviral therapy (ART) increased life expectancy of people living with HIV (PLHIV). This chronic condition was associated with other diseases with a higher risk of multiple drug use and drug interactions. Drug interactions can cause therapy failures and side effects. This cross-sectional study was carried out in three specialized clinics located in the northwestern of the state of São Paulo from September to December 2019, and evaluated the potential drug interactions in PLHIV and its impact on virological failure. PLHIV aged 50 years or older were included, using ART and other drugs for more than one year and viral load tests in the last 6 months. The data were obtained through a structured questionnaire and medical records. The interactions were analyzed by the Liverpool drug interaction database. The virological failure was defined as two exams of viral loads above 200 copies/ml. We performed a descriptive analysis of the results. Among the 113 people included in the study, 43.36% acquired the virus after