A new, atomic absorption spectrophotometric method for serum iron and iron-binding capacity is described, which utilizes 20% (w/v) TCA plus heating at 90° for 15 min. This procedure liberates the ferric iron; precipitates the protein, facilitating removal by centrifugation; and avoids significant interferences by contaminating hemoglobin iron. The method is highly specific, accurate, and has the additional feature of requiring less time than most colorimetric or atomic absorption methods employing chelation and extraction.
The College of American Pathologists Laboratory Accreditation Program expects a participant laboratory or laboratory section to be able to demonstrate that it is in compliance with the Standards for Laboratory Accreditation. The program expects laboratories to demonstrate that they are continually taking steps to identify and correct deficient areas and improve performance, in compliance with the Clinical Laboratory Improvement Amendments of 1988 regulatory requirements, particularly those pertaining to proficiency testing performance, and participating as inspectors in the accreditation process.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.