1967
DOI: 10.1016/s0022-5347(17)63071-4
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Carcinosarcoma of the Prostate: A Case Report

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1976
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Cited by 32 publications
(13 citation statements)
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“…Serum PSA concentrations at the time of the diagnosis of carcinosarcoma suggests that this assay is not valuable in early detection of tumor. Similar results have been reported for serum prostatic acid phosphatase (9,(11)(12)(13). The role of antiandrogen therapy and radiotherapy in the treatment of prostate carcinosarcoma is questionable (9).…”
Section: Discussionsupporting
confidence: 71%
“…Serum PSA concentrations at the time of the diagnosis of carcinosarcoma suggests that this assay is not valuable in early detection of tumor. Similar results have been reported for serum prostatic acid phosphatase (9,(11)(12)(13). The role of antiandrogen therapy and radiotherapy in the treatment of prostate carcinosarcoma is questionable (9).…”
Section: Discussionsupporting
confidence: 71%
“…Serum PSA levels are usually lower than expected for the tumor volume [4]. Estrogen therapy may stimulate tumor growth, as suggested by the case reported by Hamlin and Lurid [16]. In contrast to adenocarcinoma of the prostate, carcinosarcoma is generally characterized by a rapid and lethal course [2,3].…”
Section: Discussionmentioning
confidence: 99%
“…The histogenesis of prostate carcinosarcoma is not completely understood, and various interpretations have been proposed for the heterogenous components of this tumor [11][12][13][14][15][16][17]. Some investigators suggested that these tumors develop as a result of undifferentiated, totipotential neoplastic cells that undergo multiple pathways of terminal differentiation into either mesenchymal or epithelial elements.…”
Section: Introductionmentioning
confidence: 99%
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“…Morphologically, most of the prostate cancers are adenocarcinoma [1,2], although non-epithelial malignancies are known to develop in the prostate [3] with an incidence of less than 0.1% of all prostate malignancies [4]. Prostatic carcinosarcoma (PCS) which was first reported in 1967 by Hamlin and Lund [5], is an extremely rare malignancy and has very poor prognosis with a survival of approximate 7 months [6][7][8][9]. PCS is a histological mixture of adenocarcinoma and certain type(s) of sarcoma [1,2,10].…”
Section: Introductionmentioning
confidence: 99%