We investigated whether the topographically organized, categoryrelated patterns of neural response in the ventral visual pathway are a representation of sensory images or a more abstract representation of object form that is not dependent on sensory modality. We used functional MRI to measure patterns of response evoked during visual and tactile recognition of faces and manmade objects in sighted subjects and during tactile recognition in blind subjects. Results showed that visual and tactile recognition evoked category-related patterns of response in a ventral extrastriate visual area in the inferior temporal gyrus that were correlated across modality for manmade objects. Blind subjects also demonstrated category-related patterns of response in this ''visual'' area, and in more ventral cortical regions in the fusiform gyrus, indicating that these patterns are not due to visual imagery and, furthermore, that visual experience is not necessary for category-related representations to develop in these cortices. These results demonstrate that the representation of objects in the ventral visual pathway is not simply a representation of visual images but, rather, is a representation of more abstract features of object form.haptic perception ͉ fMRI ͉ supramodal cortex
Diffusion magnetic resonance imaging (MRI) is a standard imaging tool in clinical neurology, and is becoming increasingly important for neuroscience studies due to its ability to depict complex neuroanatomy (eg, white matter connectivity). Single‐shot echo‐planar imaging is currently the predominant formation method for diffusion MRI, but suffers from blurring, distortion, and low spatial resolution. A number of methods have been proposed to address these limitations and improve diffusion MRI acquisition. Here, the recent technical developments for image formation in diffusion MRI are reviewed. We discuss three areas of advance in diffusion MRI: improving image fidelity, accelerating acquisition, and increasing the signal‐to‐noise ratio.
Level of Evidence: 5
Technical Efficacy: Stage 1J. MAGN. RESON. IMAGING 2017;46:646–662
High-resolution diffusion MRI can provide the ability to resolve small brain structures, enabling investigations of detailed white matter architecture. A major challenge for in vivo high-resolution diffusion MRI is the low signal-to-noise ratio. In this work, we combine two highly compatible methods, ultra-high field and three-dimensional multi-slab acquisition to improve the SNR of high-resolution diffusion MRI. As each kz plane is encoded using a single-shot echo planar readout, scan speeds of the proposed technique are similar to the commonly used two-dimensional diffusion MRI. In-plane parallel acceleration is applied to reduce image distortions. To reduce the sensitivity of auto-calibration signal data to subject motion and respiration, several new adaptions of the fast low angle excitation echo-planar technique (FLEET) that are suitable for 3D multi-slab echo planar imaging are proposed and evaluated. A modified reconstruction scheme is proposed for auto-calibration with the most robust method, Slice-FLEET acquisition, to make it compatible with navigator correction of motion induced phase errors. Slab boundary artefacts are corrected using the nonlinear slab profile encoding method recently proposed by our group. In vivo results demonstrate that using 7T and three-dimensional multi-slab acquisition with improved auto-calibration signal acquisition and nonlinear slab boundary artefacts correction, high-quality diffusion MRI data with ~1 mm isotropic resolution can be achieved.
PurposeTo propose a method to reduce the slab boundary artifacts in three-dimensional multislab diffusion MRI.MethodsBloch simulation is used to investigate the effects of multiple factors on slab boundary artifacts, including characterization of residual errors on diffusion quantification. A nonlinear inversion method is proposed to simultaneously estimate the slab profile and the underlying (corrected) image.ResultsCorrection results of numerical phantom and in vivo data demonstrate that the method can effectively remove slab boundary artifacts for diffusion data. Notably, the nonlinear inversion is also successful at short TR, a regimen where previously proposed methods (slab profile encoding and weighted average) retain residual artifacts in both diffusion-weighted images and diffusion metrics (mean diffusion coefficient and fractional anisotropy).ConclusionThe nonlinear inversion for removing slab boundary artifacts provides improvements over existing methods, particularly at the short TRs required to maximize SNR efficiency.
The proposed method can accelerate high-resolution DTI acquisition effectively by using the sharable information among different diffusion encoding directions.
In this study, the backstepping control (BSC) design for a high-performance inverter with the functions of stand-alone and grid-connected power supply is developed so that distributed generation units can operate individually or in a micro-grid mode. In the stand-alone power-supply mode, the output ac voltage can supply to ac loads. In the grid-connected powersupply mode, the goal of power management can be achieved by controlling the amplitude and direction of the output current in the inverter. As a result, the proposed high-performance inverter with the BSC scheme has the output voltage with a low total harmonic distortion in the stand-alone power-supply mode and the output current with a high-power factor in the gridconnected power-supply mode to provide an ac output with high-performance power quality. The effectiveness of the proposed high-performance inverter with the BSC is verified by experimental results of a 3 kW prototype, and the merit of the proposed BSC scheme is indicated in comparison with previous proportional-integral control, proportional-resonant control and adaptive total sliding-mode control strategies.
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