A new germinal center kinase (GCK) family kinase, Misshapen/NIKs-related kinase (MINK), has been cloned and its expression has been characterized in several tissues and various developmental stages of the mouse brain. MINK encodes a 1300 amino acid polypeptide, consisting of an N-terminal kinase domain, a proline-rich intermediate region, and a C-terminal GCK homology region. The expression of MINK is up-regulated during the postnatal development of the mouse brain. MINK activates the cJun N-terminal kinase and the p38 pathways.z 2000 Federation of European Biochemical Societies.
In this study, OH chemiluminescence of methane-hydrogen premixed flames formed on a Bunsen burner was investigated. As for the chemiluminescence intensity, we obtained the values at the edge of the flame and at the central axis of the flame, compared with the value calculated by the inverse Abel transform. It was found that the value at the central axis of the flame was less dependent on the measurement position than that at the edge of the flame, because the effect of integrated chemiluminescence intensity on the optical path was small. In addition, four filters with different center wavelengths were tested. Although the chemiluminescence intensity was changed by the filter, the dependence of the chemiluminescence intensity on the equivalence ratio was almost the same. For more discussion, the OH concentration and the heat release rate predicted by the numerical simulation of a one-dimensional methane-hydrogen flame were compared with the OH chemiluminescence and the burning velocity in experiments. It was revealed that, even when hydrogen was added by keeping the total equivalence ratio constant, the OH chemiluminescence intensity was proportional to the production rate of excited OH* produced by the reaction of CH and O2 concentrations. Similarly, the OH chemiluminescence intensity was apparently related with the heat release rate.
In this paper, the authors discuss process planning for the lateral extrusion of a pipe with a lost core. In this process, maximum longitudinal length of the bulged part is restricted by the balance of the extrusion speed of the material and the lost core. In the free bulging condition, longitudinal length is limited to the pipe radius, because the extrusion speed of the core is slower than that of the pipe material when the longitudinal length of the bulged part is longer. The authors designed a two-stage forming process using the transit shape of a truncated cone to solve this problem. The dimensions of the truncated cone were estimated through trial-and-error using a commercial FEM simulator and considering the stretch effect for wrinkles of the pipe by deformation and traveling of the lost core. Finally, the authors conducted experiments to confirm the design’s validity. As a result, a longer longitudinal length of the bulged part than the pipe radius was successfully obtained.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.