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A novel hydrophilic analogue of parabens was synthetized and tested for its antimicrobial activity against selected microorganisms in model system. This study confirms antimicrobial potential of 1-O-(4-hydroxybenzoyl)-glycerol, which is comparable with other commercially used parabens. Unlike commercial parabens, it is possible to expect more significant antimicrobial activity of 1-O-(4-hydroxybenzoyl)-glycerol in real emulsion systems due to the increased solubility of this substance in water phase and also the lower skin irritation.

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