Objetivo: este estudo teve por objetivo descrever o perfil epidemiol�gico dos nascidos vivos residentes no munic�pio de Belo Horizonte/MG, no per�odo de 1994 a 2014. M�todo: trata-se de uma pesquisa transversal, retrospectiva, de abordagem quantitativa, realizada com base nos dados secund�rios dispon�veis no Sistema de Informa��es sobre Nascidos Vivos. Resultados: os resultados evidenciaram 738.314 nascimentos no munic�pio de Belo Horizonte/MG nesse per�odo, sendo a maioria do sexo masculino (51,1%); a termo (90,2%); com �ndice de Apgar entre 08 e 10 no primeiro minuto de vida (85%); com peso ao nascer entre 2500g e 3999g (86,4%); e sem a presen�a de anomalias cong�nitas (58,2%). Conclus�o: o Sistema de Informa��es sobre Nascidos Vivos representa um avan�o no registro de dados e serve de subs�dio para o planejamento e a implanta��o de pol�ticas p�blicas voltadas para a sa�de materno-infantil.
Resumo: Estudo quantitativo que analisou o perfil de saúde e qualidade de vida da população idosa do município de Santa Juliana-MG. Entre os207 idosos, 53,6% eram mulheres, com idade média de 70±7,5 anos. 56% vivem com companheiro e 78,7% são aposentados. A Hipertensão Arterial,a cardiopatia e doenças reumáticas foram as mais relatadas e com relação à qualidade de vida, o domínio meio ambiente era o mais prejudicado. Apesquisa aponta a necessidade de ações de promoção e educação em saúde tendo como foco o autocuidado, a prevenção de agravos e incorporandoestratégias de atenção social ao idoso.Descritores: Perfil de saúde, Idoso, Qualidade de vida.Health profile and quality of life of the elderly in Santa Juliana (MG)Abstract: Quantitative study that examined the health profile and quality of life of the elderly population of the municipality of Santa Juliana-MG.Among the 207 individuals, 53.6% were women, aged about 70 ± 7.5 years. 56% live with companion and 78.7% are retired. High blood pressure, heartdisease and rheumatic diseases were the most reported and with regard to the quality of life, the environment was the most affected. This research pointsthe need for promotional and health education focusing the self-care, prevention of diseases and social attention strategies incorporating the elderly.Descriptors: Health profile; Aged; Quality of life.Perfil de salud y calidad de vida de los ancianos de Santa Juliana (MG)Resumen: Estudio cuantitativo que examina el perfil de salud y la calidad de vida de la población anciana del municipio de Santa Juliana-MG. Entre los207 individuos, 53,6% eran mujeres, con edad media de 70 ± 7,5 años. 56% vive con acompañante y 78.7% son aposentados. La presión arterial alta,enfermedades del corazón y enfermedades reumáticas fueron las más reportadas y con respecto a la calidad de vida, el medio ambiente fue el dominiomás afectado. Esa investigación apunta la necesidad de promoción y educación para la salud centrándose en autocuidado, prevención de enfermedadesy estrategias de atención social incorporando los ancianos.Descriptores: Perfil de salud; Anciano; Calidad de vida.
Objective: analyzing the quality of life of women with gynecologic and breast cancer, undergoing antineoplasticchemotherapy for at least one year after treatment completion. Methods: a descriptive, cross-sectional study conductedin a University Hospital. To analyze quality of life, a sociodemographic and clinical data questionnaire and WHOQOL-brefwere used. Results: 30 women with an average age of 52 years were interviewed; most were diagnosed with breast cancerand received adjuvant chemotherapy. Regarding quality of life, the most negatively affected domains were the physical andpsychological domains, followed by environmental and social domains. Conclusion: including quality of life measures inclinical practice appears to be crucial in promoting comprehensive care to patients and their families.
Objetivo: analisar a evolução temporal e a qualidade das informações sobre a mortalidade neonatal em Minas Gerais. Métodos: estudo ecológico e de tendência temporal, utilizando informações relacionadas as Declaração de Óbito neonatal disponibilizadas em sistema eletrônico de domínio público no período de 1996 a 2014. Foram considerados aspectos maternos e da gestação, características do parto, do recém-nascido e aspectos relacionados ao óbito neonatal para a classificação da completude e, definição do modelo polinomial para avaliação da tendência por coeficiente de determinação e correlação de Pearson. Resultados: variáveis sexo do recém-nascido (média=0,6; IC 95% 0,5-0,7), idade do óbito (média=0,3;IC 95% 0,1-0,5) e local do óbito (média=0,3;IC 95% 0,1-0,4) apresentaram excelente completude. Modelo polinomial de primeira ordem foi determinante para explicação de tendência de redução da incompletude na maioria das variáveis (82%). Conclusão: apesar da tendência de redução da incompletude, é relevante fomentar a discussão sobre o tema, tendo em vista a melhor vigilância dos óbitos neonatais.
Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and end-stage renal failure worldwide. Several mechanisms are involved in the pathogenesis of this disease, which culminate in morphological changes such as podocyte injury. Despite the complex diagnosis and pathogenesis, limited attempts have been made to establish new biomarkers for DN. The higher concentration of Mindin protein in the urine of patients with type 2 diabetes mellitus suggests that it plays a role in DN. Therefore, this study investigated whether in situ protein expression of Mindin can be considered a potential DN biomarker. Fifty renal biopsies from patients diagnosed with DN, 57 with nondiabetic glomerular diseases, including 17 with focal segmental glomerulosclerosis (FSGS), 14 with minimal lesion disease (MLD) and 27 with immunoglobulin A nephropathy (IgAN), and 23 adult kidney samples from autopsies (control group) were evaluated for Mindin expression by immunohistochemistry. Podocyte density was inferred by Wilms’ tumor 1 (WT1) immunostaining, while foot process effacement was assessed by transmission electron microscopy. Receiver operative characteristic (ROC) analysis was performed to determine the biomarker sensitivity/specificity. Low podocyte density and increased Mindin expression were observed in all cases of DN, regardless of their class. In the DN group, Mindin expression was significantly higher than that in the FSGS, MCD, IgAN and control groups. Higher Mindin expression was significantly positively correlated with foot process effacement only in class III DN cases. Furthermore, Mindin protein presented high specificity in the biopsies of patients with DN (p < 0.0001). Our data suggest that Mindin may play a role in DN pathogenesis and is a promising biomarker of podocyte lesions.
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