The leaves, stems, and fruit of the Myrica javanica plant were obtained from the Tangkuban Perahu ABSTRACT Introduction: The presence of elastase and ROS can cause skin aging, phenolic compounds and flavonoids can be used to inhibit elastase activity and as an antioxidant. Objective: This research aimed to evaluate the anti-elastase, antioxidant activities, TPC and TFC of extracts from Myrica javanica. Methods: In this study, the leaves, stems and fruit of Myrica javanica were macerated with 96% ethanol. The extracts obtained were analysed for anti-elastase and antioxidant activities. It was also evaluated for TPC and TFC. Result: IC50 anti-elastase on leaves extract (LE), stems extract (SE), and fruits extract (FE) respectively showed 64.71 ppm, 197.49 ppm, and no activity. The anti-elastase result of three extracts are lower if compared with Myricetine (9.54 ppm). SE showed highest DPPH and TPC value (IC50=16.36 µg/mL; 307.00 mgGAE/g dry weight) and LE showed highest FRAP and TFC value (421.68 Mol/gram; 15.80 mgQE/g dry weight). Conclusion: In summary, anti-elastase and antioxidant activity are influenced by differences in the content of compounds in the extract.
Obat tradisional dapat digunakan sebagai pengobatan komplementer yang potensial untuk menjaga kesehatan atau menyembuhkan penyakit. Keberhasilan penggunaan obat tradisional salah satu faktor yang berperan adalah pengetahuan dari masyarakat mengenai obat tradisional. Mahasiswa bisa memiliki andil dalam penggunaan dan keberhasilan pengobatan dengan obat tradisional. Hal itu mendorong untuk mahasiswa memiliki pengetahuan yang baik mengenai obat tradisional termasuk dalam hal penggunaan obat tradisional. Oleh karena itu, dilakukan penelitian untuk mengetahui gambaran tingkat pengetahuan mahasiswa farmasi Poltekkes Hermina sehingga dapat mewujudkan penggunaan obat tradisional yang baik. Penelitian ini menggunakan metode Non-Eksperimental dengan desain penelitian deskriptif. Sampel sebanyak 53 responden yang memenuhi kriteria inklusi dan eksklusi mengisi kuesioner untuk mengetahui tingkat pengetahuan dalam penggunaan obat tradisional. Hasil yang diperoleh bahwa tingkat pengetahuan mahasiswa farmasi Poltekkes Hermina rendah dengan sebanyak 34 responden (64%).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.