Throughout the academic year, first-year medical students showed increased anxiety, decreased academic motivation and a maladjusted leisure/social life, which however does not seem to affect academic achievement.

It was noted that the perspective of the patient regarding their readmissions, as well as the interface with the social and familial context in which they maintain their social relationships and care for their health, was largely unexplored by the literature.

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Colorectal cancer is the leading cause of malignancy of the gastrointestinal tract. A better understanding of the molecular and cellular changes that lead to the disease is necessary to develop early diagnosis and optimal treatment modalities. Rodent models are rapid, reproducible and exhibit an adenoma-carcinoma sequence similar to that found in humans. The objective of this manuscript is to review the most common chemical carcinogens used to induce experimental tumors and the usual methods of evaluation.

Background and Aims. Patients may experience complications of Crohn’s disease (CD) even when treated with optimal medical therapy strategies. Previous data have shown the efficacy of hyperbaric oxygen therapy (HBOT) in the management of complicated CD. However, there is no consensus regarding the optimal number of sessions or duration of treatment regimens. The aim of the present study was to investigate the efficacy of HBOT in CD patients who were refractory to conventional medical management. Methods. This study included patients who underwent HBOT for the treatment of the following complications: perianal fistulizing Crohn’s disease (pCD), enterocutaneous fistulas (ECF), or pyoderma gangrenosum (PG). Complete healing was defined as the closure of external orifice and the absence of active draining (in pCD), complete wound healing (in PG), and granulation or complete wound epithelialization with no enteric draining (in ECF). The persistence of draining and the absence of wound granulation were defined as incomplete healing. Results. Forty patients were included. The mean CD duration was 10.6 ± 5.8 years. pCD comprised most of the included patients (25/62.5%), followed by ECF ( n = 13 / 32.5 % ) and PG ( n = 6 / 15 % ). In two patients (5%), a combination of ECF and PG was diagnosed, and in one patient (2.5%), all three complications were observed. A total of 32 patients (82.5%) had complete healing. Patients with PG had the highest healing rates (100%), followed by those with ECF (84.6%) and pCD (80%). Conclusions. Adjunctive HBO was associated with significant healing rates for CD-associated complications such as pCD, ECF, and PG.

RESUMO.Este estudo teve por objetivo investigar o relato das experiências vividas por pacientes reinternados em relação aos serviços substitutivos de saúde mental. Utilizou-se abordagem qualitativa com entrevistas semiestruturadas a 22 pacientes com histórico de reinternação psiquiátrica. A interpretação dos dados foi fundamentada no paradigma emergente da Atenção Psicossocial. Os participantes, embora tenham reconhecido a qualidade do atendimento prestado nos serviços substitutivos de saúde mental, relataram limitações nesses serviços, como não funcionarem dia e noite, não proporcionarem atendimento à crise, longos intervalos entre retornos, brevidade das consultas, ausência de escuta e atendimento restrito ao controle da medicação. Os participantes também sugeriram intervenções que poderiam evitar ou substituir a internação. Nota-se que a insuficiência das respostas dos serviços substitutivos cria lacunas na assistência à saúde mental que acabam sendo preenchidas forçadamente pela internação. A reinternação psiquiátrica desvela o momento de transição entre o modelo centrado médico-hospitalar e o modo de atenção psicossocial.Palavras-chave: Hospitalização psiquiátrica; atenção psicossocial; saúde mental; serviços substitutivos. THE TREATMENT OUTSIDE THE PSYCHIATRIC HOSPITAL FROM READMITTED PATIENT´S PERSPECTIVEABSTRACT. This study aimed to investigate the narratives of the experiences of patients with psychiatric readmission regarding substitutive outpatient services for mental health. A qualitative approach was used with semistructured interviews applied to 22 patients with psychiatric readmission history. Data interpretation was based on the emerging paradigm of Psychosocial Care. Although the respondents recognized the quality of care provided by substitutive outpatient services for mental health, the participants reported limitations in these services, such as non-operating 24 hours, not to provide assistance during periods of crisis, long intervals between the returns to medical queries, the brevity of the consultation, lack of listening and limited attendance to control of the medication. The participants also suggested interventions that could prevent or replace hospitalization. Therefore, it was evident that the lack of answers from substitutive/alternative services leaves a gap in mental health care, which ends up being filled by forced hospitalization. The psychiatric readmission unveils the moment of transition between the medical-hospital centered model and the model of Psychosocial Care.Key words: Psychiatric hospitalization, psychosocial care, mental health, alternative services.. TRATAMIENTO FUERA DEL HOSPITAL, EN VISTA DEL PACIENTE CON REINTERNACIÓN PSIQUIÁTRICARESUMEN. Este estudio tuvo como objetivo investigar las narrativas de las experiencias de los pacientes reinternantes respecto a los servicios de salud mental sustitutivos. Se utilizó un enfoque cualitativo con entrevistas semiestructuradas a 22 pacientes con reinternación psiquiátrica. Interpretación de los datos se basó en el paradigma ...

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This study is justified based on the large number of individuals currently institutionalized in psychiatric hospitals in Brazil, despite the current proposal for de-hospitalization. The study focused on factors involved in the refusal of de-hospitalization, based on reports by patients in a psychiatric hospital with a diagnosis of schizophrenia and preserved verbal capacity. Based on a random selection, six patients answered a semi-structured interview. The interviews were later submitted to thematic content analysis. After reading the transcriptions, the following key thematic contents were extracted: a feeling of freedom even while hospitalized, the material and subjective protection provided by the hospital, and the way institutionalized hospital life is incorporated by patients. The findings can contribute to the drafting of public policies in mental health and to the understanding of this population's subjective dynamics.