Submetido em 22/03/2011 Aceito para publicação em 03/11/2011 Resumo O objetivo deste trabalho foi descrever a morfologia macroscópica e microscopia de luz dos órgãos respiratórios do quati (Nasua nasua). Utilizou-se cinco animais provenientes do Criatório Científico CECRIMPAS (UNIfeob), os quais foram eutanasiados e fixados em solução de formaldeído a 10% para dissecação, análise e mensuração. Para microscopia de luz, os fragmentos dos órgãos respiratórios, foram processados conforme técnicas rotineiras para histologia e corados por Hematoxilina, Eosina e Azul de Toluidina. O nariz do quati está localizado em plano nasal, formato pontiagudo e voltado para cima, possui a concha etmoidal,/nasal dorsal e nasal ventral separadas pelos meatos: nasal dorsal e ventral. A laringe /possui as quatro cartilagens: aritenóide, cricoíde, epiglote e tireóide e a traqueia contém 34 anéis traqueais separados pelo ligamento traqueal, sendo internamente revestida pelo tecido epitelial pseudoestratificado ciliado. Os pulmões estão subdivididos em lobos por fissuras interlobares, o pulmão direito é dividido em quatro lobos e o esquerdo em dois, sendo este menor que o direito. Microscópicamente os brônquios primários, secundários e terciários possuem a mesma constituição de revestimento interno da traqueia. Concluímos que o aparelho respiratório do quati se assemelha aos achados descritos na literatura para os carnívoros domésticos.Palavras-chave: Morfologia, Quati, Respiratório

ResumoO quati é um animal que pertence ao Filo Chordata, à Classe Mammalia, à Ordem Carnívora e à Família Procyonidae. A característica marcante da família Procyonidae é a presença de cinco dígitos em seus membros: WRUiFLFR H SpOYLFR (VWHV DQLPDLV VmR FODVVL¿FDGRV FRPR SODQWtJUDGRV H SRGHP UHDOL]DU PRYLPHQWRV PDQXDLV em diferentes direções. Possui hábitos de subir em árvores para procriar, fugir do perigo e pernoitar.

The biosafety of innovative procedures that utilize stem cells in regenerative medicine has been addressed in several studies. Previous work has showed no tumour formation following the use of feline and human amniotic membrane-derived stem cells (AMSCs). In contrast, tumour formation was observed when canine AMSCs were utilized. These findings suggested that feline and human, but not canine, AMSCs are suitable for cell transplantation trials. This study aimed to further evaluate the feasibility of utilizing canine AMSCs for transplantation purposes as well as for felines. We

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The ERCC2 protein is an evolutionary conserved ATPdependent helicase that is associated with a TFIIH transcription factor complex and plays an important role in nucleotide excision repair. Mutations in this gene are responsible for xeroderma pigmentosum and also for Cocayne syndrome and trichothiodystrophy. Several single nucleotide polymorphisms have been identified in the ERCC2 locus. Among them, a G23591A polymorphism in the codon 312 results in an Asp ! Asn substitution in a conserved region and a A35931C polymorphism in the codon 751 results in a Lys ! Gln substitution. Because these polymorphisms have been associated with an increased risk for several types of cancers, we carried out an hospital based case-control study in a Caucasian Portuguese population to evaluate the potential role of these polymorphisms on the individual susceptibility to thyroid cancer. The results obtained did not reveal a significant association between each individual polymorphism studied (G23591A and A35931C) and an increased thyroid cancer risk, but individuals homozygous for non-wild-type variants are overrepresented in patients group. The evaluation of the different haplotypes generated by these polymorphisms showed that individuals simultaneously homozygous for rare variants of both polymorphisms have an increased risk for thyroid cancer [adjusted odds ratio (OR) 3.084; 95% confidence interval (95% CI), 1.347-7.061; P = 0.008] and for papillary thyroid -type tumors (adjusted OR, 2.997; 95% CI, 1.235-7.272; P = 0.015) but not for follicular thyroid -type tumors. These results suggest that genetic polymorphisms in this gene might be associated with individual susceptibility towards thyroid cancer, mainly papillary-type tumors, but larger studies are required to confirm these results. (Cancer Epidemiol Biomarkers Prev 2005;14(10):2407 -12)

Scientists have long been trying to understand why the Neotropical region holds the highest diversity of birds on Earth. Recently, there has been increased interest in morphological variation between and within species, and in how climate, topography, and anthropogenic pressures may explain and affect phenotypic variation. Because morphological data are not always available for many species at the local or regional scale, we are limited in our understanding of intra‐ and interspecies spatial morphological variation. Here, we present the ATLANTIC BIRD TRAITS, a data set that includes measurements of up to 44 morphological traits in 67,197 bird records from 2,790 populations distributed throughout the Atlantic forests of South America. This data set comprises information, compiled over two centuries (1820–2018), for 711 bird species, which represent 80% of all known bird diversity in the Atlantic Forest. Among the most commonly reported traits are sex (n = 65,717), age (n = 63,852), body mass (n = 58,768), flight molt presence (n = 44,941), molt presence (n = 44,847), body molt presence (n = 44,606), tail length (n = 43,005), reproductive stage (n = 42,588), bill length (n = 37,409), body length (n = 28,394), right wing length (n = 21,950), tarsus length (n = 20,342), and wing length (n = 18,071). The most frequently recorded species are Chiroxiphia caudata (n = 1,837), Turdus albicollis (n = 1,658), Trichothraupis melanops (n = 1,468), Turdus leucomelas (n = 1,436), and Basileuterus culicivorus (n = 1,384). The species recorded in the greatest number of sampling localities are Basileuterus culicivorus (n = 243), Trichothraupis melanops (n = 242), Chiroxiphia caudata (n = 210), Platyrinchus mystaceus (n = 208), and Turdus rufiventris (n = 191). ATLANTIC BIRD TRAITS (ABT) is the most comprehensive data set on measurements of bird morphological traits found in a biodiversity hotspot; it provides data for basic and applied research at multiple scales, from individual to community, and from the local to the macroecological perspectives. No copyright or proprietary restrictions are associated with the use of this data set. Please cite this data paper when the data are used in publications or teaching and educational activities.

O quati (Nasua nasua, Linnaeus, 1766), de hábito diurno, e o mão-pelada (Procyon cancrivorus, G. Cuvier, 1798), de hábito crepuscular e noturno, são espécies de mamíferos terrestres, pertencentes à família dos procionídeos, que são amplamente encontrados no território brasileiro. Para este trabalho foram utilizados três quatis e dois mãos-peladas adultos provenientes do Criatório Científico-Cecrimpas do Centro Universitário da Fundação de Ensino Octávio Bastos (Ibama 02027.003731/04-76) dos quais foram obtidas amostras de tecido das glândulas salivares parótidas coradas em H.E. para microscopia de luz. Constatou-se que a glândula parótida dos quatis e mãos-peladas possui posicionamento semelhante à dos demais carnívoros domésticos, com seus ductos se abrindo no vestíbulo oral, próximo à altura do quarto dente pré-molar superior, e que histologicamente as glândulas parótidas dos quatis e mão-peladas são constituídas por ácinos serosos, assemelhando-se à maioria dos animais domésticos, homens e roedores e diferindo dos resultados encontrados nos cães jovens, cordeiros e outros carnívoros como o furão que possuem ácinos mistos, e de alguns carnívoros, que apresentam ácinos serosos e mucosos. Conclui-se que o fato da constituição serosa dos ácinos das glândulas parótidas dos quatis e mão-peladas se assemelhar pode ser devido ao hábito alimentar onívoro compartilhado pelas duas espécies.

The yolk sac is an extra-embryonic membrane that plays an important role in early embryonic survival. It is the production site for blood cells during embryonic mammalian development and is a likely source of stem cells. The aim of this study was to identify and characterize the putative haematopoietic cells from the yolk sac of bovine embryos at different stages of gestation. The yolk sac regresses according to gestational age and embryos are characterized into groups (I-V) according to the crown-rump measurement. Groups I-III survived in culture longer and exhibited the formation of cell clusters, whereas groups IV and V could not be maintained in culture for an extended period of time. Flow-cytometry analysis revealed that groups I-III had similar characteristics, including high expression levels of the haematopoietic markers CD34, CD90 and CD117. In groups IV and V, decreases were observed in the expression levels of CD117 and CD34. Cells were found to be capable of survival post-cryopreservation and exhibited varying abilities to form colonies in a methylcellulose matrix, depending on gestational age. Cytological analysis revealed the presence of blood cells (lymphocytes and monocytes). Quantitative PCR analysis demonstrated the presence of the haematopoietic progenitor genes GATA3 and LMO2, but not RUNX1. Thus, we have successfully isolated and characterized haematopoietic cells from the bovine embryo yolk sac at varying gestational ages. This study is crucial for the understanding of the development of the haematopoietic system and the embryonic function of this organ. Copyright © 2015 John Wiley & Sons, Ltd.