Nanotechnology in modern material science is a research hot spot due to its ability to provide novel applications in the field of dentistry. Zinc Oxide Nanoparticles (ZnO NPs) are metal oxide nanoparticles that open new opportunities for biomedical applications that range from diagnosis to treatment. The domains of these nanoparticles are wide and diverse and include the effects brought about due to the anti-microbial, regenerative, and mechanical properties. The applications include enhancing the anti-bacterial properties of existing restorative materials, as an anti-sensitivity agent in toothpastes, as an anti-microbial and anti-fungal agent against pathogenic oral microflora, as a dental implant coating, to improve the anti-fungal effect of denture bases in rehabilitative dentistry, remineralizing cervical dentinal lesions, increasing the stability of local drug delivery agents and other applications.
Oregano is widely used as aromatics in food and alcohol. Oregano oil has been used in traditional medicine for decades. Oregano essential oil (OEO) is extracted from leaves from the oregano plant. Oregano is known for its antibacterial and antispasmodic properties due to its polyphenol content, which includes many flavones. The aim of the study was to assess the Anti-Inflammatory Potential of Intracanal Medicament Containing Oregano Essential Oil (OEO). The anti-inflammatory activity of an intracanal medicament containing oregano essential oil at various concentrations was evaluated using the raw 264.7 cell line. The ability of extracts to suppress nitric oxide generation by cells was used to calculate percentage inhibition. Curcumin was used as the standard. The study concluded that anti-inflammatory activity of the formulation showed IC50 value of 94.34%, and hence can be used clinically to treat infected root canals.
Cranberry extract and grape seed extract rich in proanthocyanidin are known to exhibit anticariogenic effect and effective against oral pathogens like Streptococcus mutans, Prophyromonas ginivalis, Candida albicans, urinary tract Escherichia coli, and urinary tract Enterococcus feacalis. However, the effects on oral Enterococcus. feacalis has been not reported. Hence the aim of the present study is to evaluate and compare the antibacterial, anti-inflammatory activity, micro-hardness and fracture resistance of cranberry extract and grape seed extract on the teeth.
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