Antibacterial Nanozymes: An Emerging Innovative Approach to Oral Health Management

Pushpalatha, C.; Sowmya, S; Augustine, Dominic; Kumar, Chandan; Gayathri, V.; Shakir, Arshiya; Prabhu, T. Niranjana; Sandhya, K. V.; Patil, Shankargouda

doi:10.1007/s11244-022-01731-1

Cited by 4 publications

(1 citation statement)

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“…Through biocatalytic processes, NZs have been converted into antibacterial materials of utility. There is a shortage of a comprehensive literature review concerning the use of NZs in the treatment of oral diseases, including but not limited to dental caries, dental pulp diseases, oral ulcers, peri-implantitis, oral cancer monitoring, oral bacteria and ions, soft and hard tissue regeneration [ 153 ].…”

Section: Future and Landscape Of Antibacterial Nanozymes In Dental Di...mentioning

confidence: 99%

The potential use of nanozymes as an antibacterial agents in oral infection, periodontitis, and peri-implantitis

Hosseini Hooshiar,

Badkoobeh,

Kolahdouz

et al. 2024

J Nanobiotechnol

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Several studies suggest that oral pathogenic biofilms cause persistent oral infections. Among these is periodontitis, a prevalent condition brought on by plaque biofilm. It can even result in tooth loss. Furthermore, the accumulation of germs around a dental implant may lead to peri-implantitis, which damages the surrounding bone and gum tissue. Furthermore, bacterial biofilm contamination on the implant causes soft tissue irritation and adjacent bone resorption, severely compromising dental health. On decontaminated implant surfaces, however, re-osseointegration cannot be induced by standard biofilm removal techniques such as mechanical cleaning and antiseptic treatment. A family of nanoparticles known as nanozymes (NZs) comprise highly catalytically active multivalent metal components. The most often employed NZs with antibacterial activity are those that have peroxidase (POD) activity, among other types of NZs. Since NZs are less expensive, more easily produced, and more stable than natural enzymes, they hold great promise for use in various applications, including treating microbial infections. NZs have significantly contributed to studying implant success rates and periodontal health maintenance in periodontics and implantology. An extensive analysis of the research on various NZs and their applications in managing oral health conditions, including dental caries, dental pulp disorders, oral ulcers, peri-implantitis, and bacterial infections of the mouth. To combat bacteria, this review concentrates on NZs that imitate the activity of enzymes in implantology and periodontology. With a view to the future, there are several ways that NZs might be used to treat dental disorders antibacterially. Graphical Abstract

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Section: Future and Landscape Of Antibacterial Nanozymes In Dental Di...mentioning

confidence: 99%